The Association of Patent Foramen Ovale and Atrial Fibrillation after Coronary Artery Bypass Graft Surgery

George Djaiani, Barbara Phillips-Bute, Mihai Podgoreanu, Robert H. Messier, Joseph P. Mathew, Fiona Clements, Mark F. Newman

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


Atrial fibrillation (AF) is associated with considerable morbidity and increased resource utilization after coronary artery bypass graft surgery. In this study, we sought to determine whether patent foramen ovale (PFO) and atrial septal aneurysm are associated with an increased risk of postoperative AF in this patient population. We performed a database study on 1008 patients undergoing primary coronary artery bypass graft surgery. All patients were assessed for the development of postoperative AF from the day of surgery to hospital discharge. Atrial septal defects were identified during comprehensive intraoperative transesophageal echocardiographic examination. Postoperative AF was present in 124 (12.3%) patients. Patients with AF were significantly older and had a more frequent incidence of preoperative congestive heart failure, longer cross-clamp time, and prolonged hospital length of stay. PFO was present in 72 (7.1%) and atrial septal aneurysm in 23 (2.3%) patients. In these patients, postoperative AF was present in 14 (19.4%) patients with PFO and 8 (34.8%) patients with atrial septal aneurysm. Multivariate logistic regression analysis identified that PFO (odds ratio [OR], 1.95; 1.007-3.778; P = 0.047), age (OR, 1.03; 1.015-1.053; P = 0.0004), and history of congestive heart failure (OR, 2.55; 1.671-3.900; P < 0.0001) were predictive of postoperative AF.

Original languageEnglish
Pages (from-to)585-589
Number of pages5
JournalAnesthesia and Analgesia
Issue number3
StatePublished - Mar 2004

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


Dive into the research topics of 'The Association of Patent Foramen Ovale and Atrial Fibrillation after Coronary Artery Bypass Graft Surgery'. Together they form a unique fingerprint.

Cite this