TY - JOUR
T1 - The burden of stroke in Africa
T2 - A glance at the present and a glimpse into the future
AU - Owolabi, Mayowa O.
AU - Akarolo-Anthony, Sally
AU - Akinyemi, Rufus
AU - Arnett, Donna
AU - Gebregziabher, Mulugeta
AU - Jenkins, Carolyn
AU - Tiwari, Hemant
AU - Arulogun, Oyedunni
AU - Akpalu, Albert
AU - Sarfo, Fred Stephen
AU - Obiako, Reginald
AU - Owolabi, Lukman
AU - Sagoe, Kwamena
AU - Melikam, Sylvia
AU - Adeoye, Abiodun M.
AU - Lackland, Daniel
AU - Ovbiagele, Bruce
PY - 2015/3/1
Y1 - 2015/3/1
N2 - Objective: Information on the current burden of stroke in Africa is limited. The aim of this review was to comprehensively examine the current and projected burden of stroke in Africa. Methods: We systematically reviewed the available literature (PubMed and AJOL) from January 1960 and June 2014 on stroke in Africa. Percentage change in age-adjusted stroke incidence, mortality and disability-adjusted life years (DALYs) for African countries between 1990 and 2010 were calculated from the Global Burden of Diseases (GBD) model-derived figures. Results: Community-based studies revealed an age-standardised annual stroke incidence rate of up to 316 per 100 000 population, and age-standardised prevalence rates of up to 981 per 100 000. Model-based estimates showed significant mean increases in age-standardised stroke incidence. The peculiar factors responsible for the substantial disparities in incidence velocity, ischaemic stroke proportion, mean age and case fatality compared to high-income countries remain unknown. Conclusions: While the available study data and evidence are limited, the burden of stroke in Africa appears to be increasing.
AB - Objective: Information on the current burden of stroke in Africa is limited. The aim of this review was to comprehensively examine the current and projected burden of stroke in Africa. Methods: We systematically reviewed the available literature (PubMed and AJOL) from January 1960 and June 2014 on stroke in Africa. Percentage change in age-adjusted stroke incidence, mortality and disability-adjusted life years (DALYs) for African countries between 1990 and 2010 were calculated from the Global Burden of Diseases (GBD) model-derived figures. Results: Community-based studies revealed an age-standardised annual stroke incidence rate of up to 316 per 100 000 population, and age-standardised prevalence rates of up to 981 per 100 000. Model-based estimates showed significant mean increases in age-standardised stroke incidence. The peculiar factors responsible for the substantial disparities in incidence velocity, ischaemic stroke proportion, mean age and case fatality compared to high-income countries remain unknown. Conclusions: While the available study data and evidence are limited, the burden of stroke in Africa appears to be increasing.
KW - Africa
KW - Epidemiology
KW - Incidence
KW - Mortality
KW - Prevalence
KW - Stroke
UR - https://www.scopus.com/pages/publications/84930038869
UR - https://www.scopus.com/pages/publications/84930038869#tab=citedBy
U2 - 10.5830/CVJA-2015-038
DO - 10.5830/CVJA-2015-038
M3 - Article
C2 - 25962945
AN - SCOPUS:84930038869
SN - 1995-1892
VL - 26
SP - S27-S38
JO - Cardiovascular Journal of Africa
JF - Cardiovascular Journal of Africa
IS - 2
ER -