The common metabolite glycerol-3-phosphate is a novel regulator of plant defense signaling

Srivathsa C. Venugopal, Bidisha Chanda, Lisa Vaillancourt, Aardra Kachroo, Pradeep Kachroo

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

Conversion of glycerol to glycerol-3-phosphate (G3P) is one of the highly conserved steps of glycerol metabolism in evolutionary diverse organisms. In plants, G3P is produced either via the glyc- erol kinase (GK)-mediated phosphorylation of glycerol, or via G3P dehydrogenase (G3Pdh)-mediated reduction of dihydroxy- acetone phosphate (DHAP). We have recently shown that G3P levels contribute to basal resistance against the hemibiotrophic pathogen, Colletotrichum higginsianum. Since a mutation in the GLY1-encoded G3Pdh conferred more susceptibility compared to a mutation in the GLI1-encoded GK, we proposed that GLY1 is the major contributor of the total G3P pool that participates in defense against C. higginsianum.

Original languageEnglish
Pages (from-to)746-749
Number of pages4
JournalPlant Signaling and Behavior
Volume4
Issue number8
DOIs
StatePublished - 2009

Bibliographical note

Funding Information:
This work was supported by grants from the USDA-NRI (2004-03287, 2006-01854), NSF (MCB#0421914, IOS#0749731) and the Kentucky Science and Engineering Foundation (622-RDE-006).

Keywords

  • Defense
  • Glycerol metabolism
  • Glycerol-3-phosphate
  • Signaling

ASJC Scopus subject areas

  • Plant Science

Fingerprint

Dive into the research topics of 'The common metabolite glycerol-3-phosphate is a novel regulator of plant defense signaling'. Together they form a unique fingerprint.

Cite this