TY - JOUR
T1 - The connection between heart rate variability (HRV), neurological health, and cognition
T2 - A literature review
AU - Arakaki, Xianghong
AU - Arechavala, Rebecca J.
AU - Choy, Elizabeth H.
AU - Bautista, Jayveeritz
AU - Bliss, Bishop
AU - Molloy, Cathleen
AU - Wu, Daw An
AU - Shimojo, Shinsuke
AU - Jiang, Yang
AU - Kleinman, Michael T.
AU - Kloner, Robert A.
N1 - Publisher Copyright:
Copyright © 2023 Arakaki, Arechavala, Choy, Bautista, Bliss, Molloy, Wu, Shimojo, Jiang, Kleinman and Kloner.
PY - 2023
Y1 - 2023
N2 - The heart and brain have bi-directional influences on each other, including autonomic regulation and hemodynamic connections. Heart rate variability (HRV) measures variation in beat-to-beat intervals. New findings about disorganized sinus rhythm (erratic rhythm, quantified as heart rate fragmentation, HRF) are discussed and suggest overestimation of autonomic activities in HRV changes, especially during aging or cardiovascular events. When excluding HRF, HRV is regulated via the central autonomic network (CAN). HRV acts as a proxy of autonomic activity and is associated with executive functions, decision-making, and emotional regulation in our health and wellbeing. Abnormal changes of HRV (e.g., decreased vagal functioning) are observed in various neurological conditions including mild cognitive impairments, dementia, mild traumatic brain injury, migraine, COVID-19, stroke, epilepsy, and psychological conditions (e.g., anxiety, stress, and schizophrenia). Efforts are needed to improve the dynamic and intriguing heart-brain interactions.
AB - The heart and brain have bi-directional influences on each other, including autonomic regulation and hemodynamic connections. Heart rate variability (HRV) measures variation in beat-to-beat intervals. New findings about disorganized sinus rhythm (erratic rhythm, quantified as heart rate fragmentation, HRF) are discussed and suggest overestimation of autonomic activities in HRV changes, especially during aging or cardiovascular events. When excluding HRF, HRV is regulated via the central autonomic network (CAN). HRV acts as a proxy of autonomic activity and is associated with executive functions, decision-making, and emotional regulation in our health and wellbeing. Abnormal changes of HRV (e.g., decreased vagal functioning) are observed in various neurological conditions including mild cognitive impairments, dementia, mild traumatic brain injury, migraine, COVID-19, stroke, epilepsy, and psychological conditions (e.g., anxiety, stress, and schizophrenia). Efforts are needed to improve the dynamic and intriguing heart-brain interactions.
KW - cognition
KW - erratic sinus rhythm
KW - heart and brain
KW - heart rate fragmentation
KW - heart rate variability
KW - inhibitory control
KW - neurological conditions
KW - vagal functioning
UR - http://www.scopus.com/inward/record.url?scp=85150168280&partnerID=8YFLogxK
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U2 - 10.3389/fnins.2023.1055445
DO - 10.3389/fnins.2023.1055445
M3 - Review article
AN - SCOPUS:85150168280
SN - 1662-4548
VL - 17
JO - Frontiers in Neuroscience
JF - Frontiers in Neuroscience
M1 - 1055445
ER -