Abstract
Public participation in precision medicine (PM) research is essential to achieving effective health care but has been impeded by a lack of awareness and basic knowledge. There is a critical need for educational materials that can clearly explain PM to foster involvement. This randomized controlled trial with a posttest-only control group design aims to assess the effects of educational messages delivered through animations relative to live-action videos and leaflets on intentions of involvement in PM research. Knowledge as the moderator and four mediators (engagement, vividness, trustworthiness, and cognitive value) of the intended effects were also evaluated. A total of 326 U.S. adults were sampled from Amazon Mechanical Turk. Among participants with less knowledge about PM, animations produced stronger information-seeking intentions and willingness to participate than leaflets. The effects of three message modalities were not significantly different among average and highly knowledgeable participants. Engagement and vividness mediated the effects of animations relative to two other message modalities. Trustworthiness and cognitive value mediated the effects of animations relative to live-action videos. Overall, animations can be an effective communication strategy to motivate involvement in PM but its effectiveness could decline as knowledge increases. The explanations and implications of the findings were discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 220-231 |
| Number of pages | 12 |
| Journal | Journal of Health Communication |
| Volume | 29 |
| Issue number | 3 |
| DOIs | |
| State | Published - 2024 |
Bibliographical note
Publisher Copyright:©, Copyright © Taylor & Francis Group, LLC.
Funding
We designed an experiment with three conditions, each of which featured one message modality. All messages were about participation in the All of Us Precision Medicine Initiative (PMI). This PM research program is sponsored by the U.S. government and open to the general adult population (NIH, ). Examples of the experimental messages can be found in the supplemental material. The research was supported by a grant from the Center for Communication, Culture, and Change at the University of Miami. The contents of the research are solely the responsibility of the authors. The funding source had no role in study design, collection, analysis, and interpretation of data.
| Funders |
|---|
| University of Miami Center for Communication, Culture |
| U.S. Government |
| National Institutes of Health (NIH) |
| Miami Clinical and Translational Science Institute, University of Miami |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
ASJC Scopus subject areas
- Health(social science)
- Communication
- Public Health, Environmental and Occupational Health
- Library and Information Sciences
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