The effects of depression on the treatment of OCD in a residential sample

Chad T. Wetterneck, Rachel C. Leonard, Thomas G. Adams, Bradley C. Riemann, Peter Grau, Martin E. Franklin

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Studies investigating the impact of depressive symptoms on obsessive-compulsive disorder (OCD) treatment have yielded mixed findings. The purpose of the study is to extend previous research, which primarily used outpatient samples, to determine whether depression affects OCD treatment outcome among patients receiving intensive residential treatment. OCD patients receiving residential treatment based primarily on exposure and response prevention (ERP) provided data regarding symptoms of depression and OCD at admission and discharge. Patients reported large and significant reductions in OCD symptoms over the course of treatment. Change in OCD symptoms was not significantly affected by depressive symptoms, including patients with severe depressive symptoms. Change in depressive symptoms over the course of treatment was, however, robustly related to change in OCD symptoms, especially among patients who began treatment with severe symptoms of depression. These findings suggest that cognitive-behavior therapy delivered in a residential treatment setting drastically reduces OCD symptoms regardless of depressive symptoms.

Original languageEnglish
Pages (from-to)12-33
Number of pages22
JournalBulletin of the Menninger Clinic
StatePublished - 2020

Bibliographical note

Publisher Copyright:
© 2020 The Menninger Foundation


  • Depression
  • Exposure and ritual prevention
  • Intensive treatment
  • Obsessive-compulsive disorder

ASJC Scopus subject areas

  • Psychiatric Mental Health
  • Clinical Psychology
  • Psychiatry and Mental health


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