The effects of withaferin a on normal and malignant immune cells

Sara S. Alhakeem; Mary K. McKenna; Karine Z. Oben; Beth W. Gachuki; Sunil K. Noothi; Natarajan Muthusamy; Vivek M. Rangnekar; Ramesh C. Gupta; Subbarao Bondada

doi:10.1007/978-3-319-59192-6_11

The effects of withaferin a on normal and malignant immune cells

Sara S. Alhakeem, Mary K. McKenna, Karine Z. Oben, Beth W. Gachuki, Sunil K. Noothi, Natarajan Muthusamy, Vivek M. Rangnekar, Ramesh C. Gupta, Subbarao Bondada

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Ashwagandha, an ayurvedic medicinal plant, has been found to be a major contributor in treating medical ailments. Ayurveda is one of the world's oldest traditional medical systems originated in India through various indigenous theories, beliefs and experiences. Often translated as science of "ayus" (life) and "ved" (knowledge), it emphasizes the use of herbs and their derivatives for prevention of disease, rejuvenation of body systems, and improving the quality of life. In this chapter, we will discuss some of the immuno-modulatory effects of withaferin A (WFA) as well as its growth-inhibitory effects on B cell lymphoma, leukemia and myelodysplastic syndrome.

Original language	English
Title of host publication	Science of Ashwagandha
Subtitle of host publication	Preventive and Therapeutic Potentials
Pages	227-242
Number of pages	16
ISBN (Electronic)	9783319591926
DOIs	https://doi.org/10.1007/978-3-319-59192-6_11
State	Published - Sep 13 2017

Bibliographical note

Publisher Copyright:
© Springer International Publishing AG 2017. All rights are reserved.

Keywords

B cell lymphoma
Growth-inhibitory effects
Immuno-modulatory effects
Withaferin A
Withania somnifera

ASJC Scopus subject areas

General Medicine
General Social Sciences

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10.1007/978-3-319-59192-6_11

Cite this

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AU - Noothi, Sunil K.

AU - Muthusamy, Natarajan

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AU - Gupta, Ramesh C.

AU - Bondada, Subbarao

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The effects of withaferin a on normal and malignant immune cells

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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Cite this