The equine immune responses to infectious and allergic disease: A model for humans?

David W. Horohov

Research output: Contribution to journalReview articlepeer-review

28 Scopus citations

Abstract

The modern horse, Equus caballus has historically made important contributions to the field of immunology, dating back to Emil von Behring's description of curative antibodies in equine serum over a century ago. While the horse continues to play an important role in human serotherapy, the mouse has replaced the horse as the predominant experimental animal in immunology research. Nevertheless, continuing efforts have led to an improved understanding of the equine immune response in a variety of infectious and non-infectious diseases. Based on this information, we can begin to identify specific situations where the horse may provide a unique immunological model for certain human diseases.

Original languageEnglish
Pages (from-to)89-96
Number of pages8
JournalMolecular Immunology
Volume66
Issue number1
DOIs
StatePublished - Jul 1 2015

Bibliographical note

Publisher Copyright:
© 2014 Elsevier Ltd.

Keywords

  • Allergy
  • Equine
  • Immunity
  • Infectious disease

ASJC Scopus subject areas

  • Immunology
  • Molecular Biology

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