The evolving concept of margins in musculoskeletal oncology

The surgical margin in musculoskeletal oncology is a complex idea that has evolved over time owing to improved adjuvant treatment and a better understanding of the biology of sarcomas. The historical surgical concepts of "wide" or "2. cm" margins are no longer appropriate. Today's musculoskeletal oncologist must balance the aggressivity of the surgical resection against the morbidity associated with that resection. Presented herein are both an introduction and an advanced look into the status and data supporting the concept of the surgical margin in musculoskeletal oncology.