The Experimental Approach to Alcoholism

J. M. Littleton

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


The author discusses the biochemical basis of physical and psychological dependence on ethanol, with particular reference to the role of acetaldehyde, monoamines and amino acids. Preliminary results are presented in which the factors of environment, heredity, sex, age and diet are shown to affect susceptibility of mice to ethanol dependence, and an attempt is made to relate the influence of these factors to the biochemical basis of dependence.

Original languageEnglish
Pages (from-to)99-122
Number of pages24
JournalBritish Journal of Addiction to Alcohol & Other Drugs
Issue number2
StatePublished - Jun 1975

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Psychiatry and Mental health


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