Abstract
The first reagent-controlled asymmetric halolactonizations are described. Complexes of I+ with O-acyl- and O-aryldihydroquinidines are used to promote the asymmetric halolactonization of prochiral Γ,δ-unsaturated carboxylic acids with low but measurable and reproducible enantioselectivity. Experimental factors affecting the ee's are described.
Original language | English |
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Pages (from-to) | 1233-1237 |
Number of pages | 5 |
Journal | Canadian Journal of Chemistry |
Volume | 76 |
Issue number | 9 |
DOIs | |
State | Published - 1998 |
Keywords
- Chiral
- Halocyclization
- Halogenation
- Halonium ions
- Stereoselective
ASJC Scopus subject areas
- Catalysis
- General Chemistry
- Organic Chemistry