The management of acute and chronic pancreatitis

Peter A. Banks, Darwin L. Conwell, Phillip P. Toskes

Research output: Contribution to journalArticlepeer-review

56 Scopus citations

Abstract

Pancreatitis, which is most generally described as any inflammation of the pancreas, is a serious condition that manifests in either acute or chronic forms. Chronic pancreatitis results from irreversible scarring of the pancreas, resulting from prolonged inflammation. Six major etiologies for chronic pancreatitis have been identified: toxic/metabolic, idiopathic, genetic, autoimmune, recurrent and severe acute pancreatitis, and obstruction. The most common symptom associated with chronic pancreatitis is pain localized to the upper-to-middle abdomen, along with food malabsorption, and eventual development of diabetes. Treatment strategies for acute pancreatitis include fasting and short-term intravenous feeding, fluid therapy, and pain management with narcotics for severe pain or nonsteroidal anti-inflammatories for milder cases. Patients with chronic disease and symptoms require further care to address digestive issues and the possible development of diabetes. Dietary restrictions are recommended, along with enzyme replacement and vitamin supplementation. More definitive outcomes may be achieved with surgical or endoscopic methods, depending on the role of the pancreatic ducts in the manifestation of disease.

Original languageEnglish
Pages (from-to)1-9
Number of pages9
JournalGastroenterology and Hepatology
Volume6
Issue number2
StatePublished - Feb 2010

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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