@article{ecf7b2f25f624cccaf9909a9664db93d,
title = "The mating-type locus Bα1 of Schizophyllum commune contains a pheromone receptor gene and putative pheromone genes",
abstract = "Analysis of the multispecific Bα mating-type locus of Schizophyllum commune provided evidence that pheromones and pheromone receptors govern recognition of self versus non-self and sexual development in this homobasidiomycetous fungus. Four subclones of an 8.2 kb genomic fragment carrying Bα1 specificity induced B-regulated sexual morphogenesis when introduced into a strain with one of the eight compatible Bα specificities that are known to exist in nature. One of these clones, which activated all other Bα specificities, contains a gene termed bar1. The predicted protein product of bar1, as well as that of bar2, a homologous gene isolated from a Bα2 strain, has significant homology to known fungal pheromone receptor proteins in the rhodopsin-like superfamily of G protein-linked receptors. The other three active Bα1 clones were subcloned further to identify the minimal active element in each clone. Every active subclone contains a putative pheromone gene ending in a signal for possible isoprenylation. A message of ~600 bp was observed for one of these genes, bap1(1). This paper presents the first evidence for a system of multiple pheromones and pheromone receptors as a basis for multispecific mating types in a fungus.",
keywords = "Basidiomycete, Development, G protein-coupled receptor, Mating type, Pheromones",
author = "J. Wendland and Vaillancourt, {L. J.} and J. Hegner and Lengeler, {K. B.} and Laddison, {K. J.} and Specht, {C. A.} and Raper, {C. A.} and E. Kothe",
year = "1995",
doi = "10.1002/j.1460-2075.1995.tb00211.x",
language = "English",
volume = "14",
pages = "5271--5278",
number = "21",
}