The novel small molecule α9α10 nicotinic acetylcholine receptor antagonist ZZ-204G is analgesic

Medicine and Dentistry

• Anodyne 100%
• Nicotinic Receptor 100%
• Nicotinic Acetylcholine Receptor Antagonist 100%
• Neuropathic Pain 50%
• Peptide 33%
• Assay 33%
• Tail 33%
• Gamma-Aminobutyric Acid 33%
• Formaldehyde 33%
• Chronic Constriction Injury 33%
• Oocyte 16%
• Low Drug Dose 16%
• Chronic Pain 16%
• Parenteral Drug Administration 16%
• κ-Opioid Receptor 16%
• Serotonin 16%
• Motor Performance 16%
• Paw 16%
• Nociception 16%
• Inflammatory Pain 16%
• Competitive Binding Assay 16%
• Quaternary Ammonium Derivative 16%
• Mechanical Hyperalgesia 16%
• Molecular Scaffold 16%

Biochemistry, Genetics and Molecular Biology

• Small Molecule 100%
• Receptor Antagonist 100%
• Nicotinic Receptor 100%
• Nicotinic Acetylcholine Receptor 100%
• Peptide 40%
• Electric Potential 20%
• Dose 20%
• Low Drug Dose 20%
• Serotonin 20%
• Rat Model 20%
• Opioid Receptor 20%
• IC50 20%
• Xenopus 20%
• Motor Performance 20%
• Binding Competition 20%
• Rotarod Test 20%
• Nociception 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Analgesic Agent 100%
• Nicotinic Receptor 100%
• Neuropathic Pain 50%
• Peptide 33%
• 4 Aminobutyric Acid 33%
• Formaldehyde 33%
• Rat Model 16%
• Opiate Receptor 16%
• Chronic Pain 16%
• Serotonin 16%
• Quaternary Ammonium Derivative 16%
• Xenopus 16%
• Inflammatory Pain 16%
• Molecular Scaffold 16%
• Mechanical Hyperalgesia 16%
• Chronic Inflammatory Pain 16%