The Oxidative Decyanation of Secondary Nitriles via α-Hydroperoxynitriles

Sandra J. Selikson; David S. Watt

doi:10.1021/jo00890a032

The Oxidative Decyanation of Secondary Nitriles via α-Hydroperoxynitriles

Sandra J. Selikson
, David S. Watt

Molecular and Cellular Biochemistry

Research output: Contribution to journal › Letter › peer-review

100 Scopus citations

Abstract

The oxidative decyanation of secondary nitriles to ketones was effected by trapping nitrile anions with molecular oxygen, reducing the resulting α-hydroperoxynitriles to cyanohydrins with stannous chloride, and converting the cyanohydrins to ketones with sodium hydroxide.

Original language	English
Pages (from-to)	267-268
Number of pages	2
Journal	Journal of Organic Chemistry
Volume	40
Issue number	2
DOIs	https://doi.org/10.1021/jo00890a032
State	Published - Jan 1 1975

ASJC Scopus subject areas

Organic Chemistry

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title = "The Oxidative Decyanation of Secondary Nitriles via α-Hydroperoxynitriles",

abstract = "The oxidative decyanation of secondary nitriles to ketones was effected by trapping nitrile anions with molecular oxygen, reducing the resulting α-hydroperoxynitriles to cyanohydrins with stannous chloride, and converting the cyanohydrins to ketones with sodium hydroxide.",

author = "Selikson, \{Sandra J.\} and Watt, \{David S.\}",

year = "1975",

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T1 - The Oxidative Decyanation of Secondary Nitriles via α-Hydroperoxynitriles

AU - Selikson, Sandra J.

AU - Watt, David S.

PY - 1975/1/1

Y1 - 1975/1/1

N2 - The oxidative decyanation of secondary nitriles to ketones was effected by trapping nitrile anions with molecular oxygen, reducing the resulting α-hydroperoxynitriles to cyanohydrins with stannous chloride, and converting the cyanohydrins to ketones with sodium hydroxide.

AB - The oxidative decyanation of secondary nitriles to ketones was effected by trapping nitrile anions with molecular oxygen, reducing the resulting α-hydroperoxynitriles to cyanohydrins with stannous chloride, and converting the cyanohydrins to ketones with sodium hydroxide.

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UR - https://www.scopus.com/pages/publications/33847802830#tab=citedBy

U2 - 10.1021/jo00890a032

DO - 10.1021/jo00890a032

M3 - Letter

AN - SCOPUS:33847802830

SN - 0022-3263

VL - 40

SP - 267

EP - 268

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 2

ER -

The Oxidative Decyanation of Secondary Nitriles via α-Hydroperoxynitriles

Abstract

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