The regulation of plant vegetative phase transition and rejuvenation: Mirnas, a key regulator

Tajbir Raihan, Robert L. Geneve, Sharyn E. Perry, Carlos M.Rodriguez Lopez

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


In contrast to animals, adult organs in plants are not formed during embryogenesis but generated from meristematic cells as plants advance through development. Plant development involves a succession of different phenotypic stages and the transition between these stages is termed phase transition. Phase transitions need to be tightly regulated and coordinated to ensure they occur under optimal seasonal, environmental conditions. Polycarpic perennials transition through vegetative stages and the mature, reproductive stage many times during their lifecycles and, in both perennial and annual species, environmental factors and culturing methods can reverse the otherwise unidirectional vector of plant development. Epigenetic factors regulating gene expression in response to internal cues and external (environmental) stimuli influencing the plant’s phenotype and development have been shown to control phase transitions. How developmental and environmental cues interact to epigenetically alter gene expression and influence these transitions is not well understood, and understanding this interaction is important considering the current climate change scenarios, since epigenetic maladaptation could have catastrophic consequences for perennial plants in natural and agricultural ecosystems. Here, we review studies focusing on the epigenetic regulators of the vegetative phase change and highlight how these mechanisms might act in exogenously induced plant rejuvenation and regrowth following stress.

Original languageEnglish
Article number24
Issue number4
StatePublished - Dec 2021

Bibliographical note

Funding Information:
Funding: C.M.R.L. is partially supported by the National Institute of Food and Agriculture, AFRI Competitive Grant Program Accession number 1018617 and National Institute of Food and Agriculture, United States Department of Agriculture, Hatch Program accession number 1020852. The funding agencies did not have any role in writing the manuscript.

Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.


  • Epigenetics
  • Phase change
  • Rejuvenation
  • Vegetative

ASJC Scopus subject areas

  • Biochemistry
  • Biochemistry, Genetics and Molecular Biology (miscellaneous)
  • Genetics
  • Health, Toxicology and Mutagenesis


Dive into the research topics of 'The regulation of plant vegetative phase transition and rejuvenation: Mirnas, a key regulator'. Together they form a unique fingerprint.

Cite this