The Role of Glutamate Dysregulation in the Etiology of ADHD

P. E.A. Glaser; S. R. Batten; G. A. Gerhardt

doi:10.1007/978-3-030-87480-3_16

The Role of Glutamate Dysregulation in the Etiology of ADHD

P. E.A. Glaser, S. R. Batten, G. A. Gerhardt

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Scopus citations

Abstract

In this chapter we review current data assessing the role of glutamate in the etiology of ADHD. A general introduction of ADHD and common comorbidities are briefly discussed. The glutamate system in general and its potential role in ADHD are thoroughly reviewed evaluating both preclinical and clinical data. The current ADHD treatments that act on the glutamate system, memantine and atomoxetine, are discussed. The chapter concludes with a discussion on the future of glutamatergic drugs in the treatment of ADHD.

Original language	English
Title of host publication	Glutamate and Neuropsychiatric Disorders
Subtitle of host publication	Current and Emerging Treatments
Pages	467-492
Number of pages	26
ISBN (Electronic)	9783030874803
DOIs	https://doi.org/10.1007/978-3-030-87480-3_16
State	Published - Jan 1 2022

Bibliographical note

Publisher Copyright:
© Springer Nature Switzerland AG 2022.

Keywords

ADHD
Brain energetics
Glutamate
Glutamatergic pharmacotherapies

ASJC Scopus subject areas

General Medicine
General Neuroscience

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10.1007/978-3-030-87480-3_16

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AB - In this chapter we review current data assessing the role of glutamate in the etiology of ADHD. A general introduction of ADHD and common comorbidities are briefly discussed. The glutamate system in general and its potential role in ADHD are thoroughly reviewed evaluating both preclinical and clinical data. The current ADHD treatments that act on the glutamate system, memantine and atomoxetine, are discussed. The chapter concludes with a discussion on the future of glutamatergic drugs in the treatment of ADHD.

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The Role of Glutamate Dysregulation in the Etiology of ADHD

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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