Abstract
Our view of microglia has dramatically changed in the last decade. From cells being "silent" in the healthy brain, microglia have emerged to be actively involved in several brain physiological functions including adult hippocampal neurogenesis, and cognitive and behavioral function. In light of recent discoveries revealing a role of microglia as important effectors of neuronal circuit reorganization, considerable attention has been focused on how microglia and hippocampal neurogenesis could be an interdependent phenomenon. In this review the role of microglia in the adult hippocampal neurogenesis under physiological condition is discussed.
| Original language | English |
|---|---|
| Article number | 229 |
| Journal | Frontiers in Cellular Neuroscience |
| Volume | 7 |
| Issue number | NOV |
| DOIs | |
| State | Published - Nov 22 2013 |
Bibliographical note
Copyright:Copyright 2014 Elsevier B.V., All rights reserved.
Keywords
- CX3CR1
- Chemokines
- Fractalkine
- Microglia
- Neurogenesis
ASJC Scopus subject areas
- Cellular and Molecular Neuroscience