The structure of mithramycin reinvestigated

S. E. Wohlert; E. Künzel; R. Machinek; C. Méndez; J. A. Salas; J. Rohr

doi:10.1021/np980355k

The structure of mithramycin reinvestigated

S. E. Wohlert, E. Künzel, R. Machinek, C. Méndez, J. A. Salas, J. Rohr

Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

70 Scopus citations

Abstract

A reinvestigation of the structure of mithramycin, the principal product of Streptomyces argillaceus ATCC 12956, is reported. The structure elucidation was carried out with mithramycin decaacetate (4) using 2D NMR methods, including TOCSY, HMBC, and HSQC experiments. The work resulted in structure 3 being confirmed for mithramycin.

Original language	English
Pages (from-to)	119-121
Number of pages	3
Journal	Journal of Natural Products
Volume	62
Issue number	1
DOIs	https://doi.org/10.1021/np980355k
State	Published - 1999

ASJC Scopus subject areas

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

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10.1021/np980355k

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title = "The structure of mithramycin reinvestigated",

abstract = "A reinvestigation of the structure of mithramycin, the principal product of Streptomyces argillaceus ATCC 12956, is reported. The structure elucidation was carried out with mithramycin decaacetate (4) using 2D NMR methods, including TOCSY, HMBC, and HSQC experiments. The work resulted in structure 3 being confirmed for mithramycin.",

author = "Wohlert, {S. E.} and E. K{\"u}nzel and R. Machinek and C. M{\'e}ndez and Salas, {J. A.} and J. Rohr",

year = "1999",

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T1 - The structure of mithramycin reinvestigated

AU - Wohlert, S. E.

AU - Künzel, E.

AU - Machinek, R.

AU - Méndez, C.

AU - Salas, J. A.

AU - Rohr, J.

PY - 1999

Y1 - 1999

N2 - A reinvestigation of the structure of mithramycin, the principal product of Streptomyces argillaceus ATCC 12956, is reported. The structure elucidation was carried out with mithramycin decaacetate (4) using 2D NMR methods, including TOCSY, HMBC, and HSQC experiments. The work resulted in structure 3 being confirmed for mithramycin.

AB - A reinvestigation of the structure of mithramycin, the principal product of Streptomyces argillaceus ATCC 12956, is reported. The structure elucidation was carried out with mithramycin decaacetate (4) using 2D NMR methods, including TOCSY, HMBC, and HSQC experiments. The work resulted in structure 3 being confirmed for mithramycin.

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DO - 10.1021/np980355k

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ER -

The structure of mithramycin reinvestigated

Abstract

ASJC Scopus subject areas

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