The structure of mithramycin reinvestigated

S. E. Wohlert, E. Künzel, R. Machinek, C. Méndez, J. A. Salas, J. Rohr

Research output: Contribution to journalArticlepeer-review

69 Scopus citations

Abstract

A reinvestigation of the structure of mithramycin, the principal product of Streptomyces argillaceus ATCC 12956, is reported. The structure elucidation was carried out with mithramycin decaacetate (4) using 2D NMR methods, including TOCSY, HMBC, and HSQC experiments. The work resulted in structure 3 being confirmed for mithramycin.

Original languageEnglish
Pages (from-to)119-121
Number of pages3
JournalJournal of Natural Products
Volume62
Issue number1
DOIs
StatePublished - 1999

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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