The structures of premithramycinone and demethylpremithramycinone, plausible early intermediates of the aureolic acid group antibiotic mithramycin

Jürgen Rohr

doi:10.1039/a707446h

The structures of premithramycinone and demethylpremithramycinone, plausible early intermediates of the aureolic acid group antibiotic mithramycin

Jürgen Rohr

Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

The structures of premithramycinone and its demethyl analogue suggest that the aureolic acid antibiotics are biosynthetically formed via a tetracycline-type, and not a tetracenomycin-type, folded decaketide.

Original language	English
Pages (from-to)	437-438
Number of pages	2
Journal	Chemical Communications
Issue number	3
DOIs	https://doi.org/10.1039/a707446h
State	Published - Feb 7 1998

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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title = "The structures of premithramycinone and demethylpremithramycinone, plausible early intermediates of the aureolic acid group antibiotic mithramycin",

abstract = "The structures of premithramycinone and its demethyl analogue suggest that the aureolic acid antibiotics are biosynthetically formed via a tetracycline-type, and not a tetracenomycin-type, folded decaketide.",

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The structures of premithramycinone and demethylpremithramycinone, plausible early intermediates of the aureolic acid group antibiotic mithramycin

Abstract

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