Work of breathing (WOB) functions associated with the mechanics of breathing are identified, based on a nonlinear model of the human lung and using a Lagrangian approach. Total and dissipative WOB values are computed numerically for three spontaneous breathing maneuvers (tidal, panting and forced vital capacity) of the same subject. An additional simulation reveals the effect of changing lung tissue compliance on WOB. The energy analysis provides valuable insight into the mechanics of respiration. and, in particular, the significance of individual model components. It provides the basis for sensitivity and optimization studies of the respiratory function, especially in the context of evaluating ventilator-dependent patients.
|Title of host publication||Dynamic Systems and Control|
|Number of pages||6|
|State||Published - 1997|
|Event||ASME 1997 International Mechanical Engineering Congress and Exposition, IMECE 1997 - Dynamic Systems and Control - Dallas, United States|
Duration: Nov 16 1997 → Nov 21 1997
|Name||ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)|
|Conference||ASME 1997 International Mechanical Engineering Congress and Exposition, IMECE 1997 - Dynamic Systems and Control|
|Period||11/16/97 → 11/21/97|
Bibliographical notePublisher Copyright:
© 1997 American Society of Mechanical Engineers (ASME). All rights reserved.
ASJC Scopus subject areas
- Mechanical Engineering