Therapeutics for Equine Protozoal Myeloencephalitis

Nicola Pusterla, Thomas Tobin

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


Equine protozoal myeloencephalitis is an infectious disease of the central nervous system caused by Sarcocystis neurona or Neospora hughesi. Affected horses routinely present with progressive and asymmetrical neurologic deficits. The diagnosis relies on the presence of neurologic signs, ruling out other neurologic disorders, and the detection of intrathecally derived antibodies to either S neurona and/or N hughesi. Recommended treatment is use of an FDA-approved anticoccidial drug formulation. Medical and supportive treatment is provided based on the severity of neurologic deficits and complications. This article focuses on recent data related to diagnosis, pharmacologic treatment, and prevention.

Original languageEnglish
Pages (from-to)87-97
Number of pages11
JournalVeterinary Clinics of North America - Equine Practice
Issue number1
StatePublished - Apr 1 2017

Bibliographical note

Publisher Copyright:
© 2016 Elsevier Inc.


  • Equine protozoal myeloencephalitis (EPM)
  • Neospora hughesi
  • Prevention
  • Sarcocystis neurona
  • Treatment

ASJC Scopus subject areas

  • Equine


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