Thyroxine-induced metamorphosis in the Axolotl (Ambystoma mexicanum)

Peggy S. Coots; Ashley W. Seifert

doi:10.1007/978-1-4939-2495-0_11

Thyroxine-induced metamorphosis in the Axolotl (Ambystoma mexicanum)

Peggy S. Coots, Ashley W. Seifert

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

The axolotl (Ambystoma mexicanum) has remained an important model for regeneration and developmental biology for over a century. Although axolotls in captive-bred colonies usually exist in an aquatic form, they retain the ability to undergo metamorphosis following exposure to thyroid hormone. Here we present a robust method for inducing metamorphosis in adult axolotls that results in high survivability and produces terrestrial animals that can be maintained in long-term captivity.

Original language	English
Pages (from-to)	141-145
Number of pages	5
Journal	Methods in Molecular Biology
Volume	1290
DOIs	https://doi.org/10.1007/978-1-4939-2495-0_11
State	Published - 2015

Bibliographical note

Publisher Copyright:
© Springer Science+Business Media New York 2015

Keywords

Ambystoma
Axolotl
Metamorphosis
Regeneration
Salamander
T
Thyroid hormone
Thyroxine

ASJC Scopus subject areas

Molecular Biology
Genetics

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10.1007/978-1-4939-2495-0_11

Cite this

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title = "Thyroxine-induced metamorphosis in the Axolotl (Ambystoma mexicanum)",

abstract = "The axolotl (Ambystoma mexicanum) has remained an important model for regeneration and developmental biology for over a century. Although axolotls in captive-bred colonies usually exist in an aquatic form, they retain the ability to undergo metamorphosis following exposure to thyroid hormone. Here we present a robust method for inducing metamorphosis in adult axolotls that results in high survivability and produces terrestrial animals that can be maintained in long-term captivity.",

keywords = "Ambystoma, Axolotl, Metamorphosis, Regeneration, Salamander, T, Thyroid hormone, Thyroxine",

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year = "2015",

doi = "10.1007/978-1-4939-2495-0_11",

language = "English",

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AU - Seifert, Ashley W.

N1 - Publisher Copyright: © Springer Science+Business Media New York 2015

PY - 2015

Y1 - 2015

N2 - The axolotl (Ambystoma mexicanum) has remained an important model for regeneration and developmental biology for over a century. Although axolotls in captive-bred colonies usually exist in an aquatic form, they retain the ability to undergo metamorphosis following exposure to thyroid hormone. Here we present a robust method for inducing metamorphosis in adult axolotls that results in high survivability and produces terrestrial animals that can be maintained in long-term captivity.

AB - The axolotl (Ambystoma mexicanum) has remained an important model for regeneration and developmental biology for over a century. Although axolotls in captive-bred colonies usually exist in an aquatic form, they retain the ability to undergo metamorphosis following exposure to thyroid hormone. Here we present a robust method for inducing metamorphosis in adult axolotls that results in high survivability and produces terrestrial animals that can be maintained in long-term captivity.

KW - Ambystoma

KW - Axolotl

KW - Metamorphosis

KW - Regeneration

KW - Salamander

KW - T

KW - Thyroid hormone

KW - Thyroxine

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AN - SCOPUS:84924585789

SN - 1064-3745

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SP - 141

EP - 145

JO - Methods in Molecular Biology

JF - Methods in Molecular Biology

ER -

Thyroxine-induced metamorphosis in the Axolotl (Ambystoma mexicanum)

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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