Timing of Maximal Weight Reduction Following Bariatric Surgery: A Study in Chinese Patients

Ting Xu, Chen Wang, Hongwei Zhang, Xiaodong Han, Weijie Liu, Junfeng Han, Haoyong Yu, Jin Chen, Pin Zhang, Jianzhong Di

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Introduction: Bariatric surgery is a well-received treatment for obesity with maximal weight loss at 12–36 months postoperatively. We investigated the effect of early bariatric surgery on weight reduction of Chinese patients in accordance with their preoperation characteristics. Materials and Methods: Altogether, 409 patients with obesity from a prospective cohort in a single bariatric center were enrolled retrospectively and evaluated for up to 4 years. Measurements obtained included surgery type, duration of diabetic condition, besides the usual body mass index data tuple. Weight reduction was expressed as percent total weight loss (%TWL) and percent excess weight loss (%EWL). Results: RYGB or SG were performed laparoscopically without mortality or complications. BMI generally plateaued at 12 months, having decreased at a mean of 8.78 kg/m2. Successful weight loss of >25% TWL was achieved by 35.16, 49.03, 39.22, 27.74, 20.83% of patients at 6, 12, 24, 36, and 48 months after surgery. Overall, 52.91% of our patients had lost 100% of their excess weight at 12 months, although there was a rather wide range among individuals. Similar variability was revealed in women of child-bearing age. Conclusion: Chinese patients undergoing bariatric surgery tend to achieve maximal weight loss and stabilization between 12 and 24 months postoperatively, instead of at >2 years. The finding of the shorter stabilization interval has importance to earlier intervention of weight loss related conditions and women's conception planning.

Original languageEnglish
Article number615
JournalFrontiers in Endocrinology
StatePublished - Sep 15 2020

Bibliographical note

Funding Information:
Funding. This study was supported by a clinical retrospective study of the Sixth People's Hospital Affiliated to Shanghai Jiaotong University, The middle-term efficacy of RYGB and SG in improving metabolic disorders (grant number: YNHG201912) and Tibet Autonomous Region Science and Technology Agency Project (grant number: XZ2017ZR-ZY014).

Publisher Copyright:
© Copyright © 2020 Xu, Wang, Zhang, Han, Liu, Han, Yu, Chen, Zhang and Di.


  • Chinese patients
  • bariatric surgery
  • follow up
  • trend
  • weight reduction

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism


Dive into the research topics of 'Timing of Maximal Weight Reduction Following Bariatric Surgery: A Study in Chinese Patients'. Together they form a unique fingerprint.

Cite this