Tiny dancers: The integrin-growth factor nexus in angiogenic signaling

Susan S. Smyth, Cam Patterson

Research output: Contribution to journalShort surveypeer-review

52 Scopus citations

Abstract

A vital step in growth factor-driven angiogenesis is the coordinated engagement of endothelial integrins with the extracellular matrix. The molecular mechanisms that partner growth factors and integrins are being elucidated, revealing an intricate interaction of surface receptors and their signaling pathways.

Original languageEnglish
Pages (from-to)17-21
Number of pages5
JournalJournal of Cell Biology
Volume158
Issue number1
DOIs
StatePublished - Jul 8 2002

Funding

FundersFunder number
National Heart, Lung, and Blood Institute (NHLBI)R01HL061656

    Keywords

    • Angiogenesis
    • Growth factor receptors
    • Growth factors
    • Integrins
    • Signal transduction pathways

    ASJC Scopus subject areas

    • Cell Biology

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