Abstract
Soft and hard tissue engineering has expanded the frontiers of oral/maxillofacial augmentation. Soft tissue grafting enhancements include improving flap prevascularization and using stem cells and other cells to create not only the graft, but also the vascularization and soft tissue scaffolding for the graft. Hard tissue grafts have been enhanced by osteoinductive factors, such as bone morphogenic proteins, that have allowed the elimination of harvesting autogenous bone and thus decrease the need for other surgical sites. Advancements in bone graft scaffolds have developed via seeding with stem cells and improvement of the silica/calcium/phosphate composite to improve graft characteristics and healing.
Original language | English |
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Pages (from-to) | 433-445 |
Number of pages | 13 |
Journal | Dental Clinics of North America |
Volume | 63 |
Issue number | 3 |
DOIs | |
State | Published - Jul 2019 |
Bibliographical note
Publisher Copyright:© 2019 Elsevier Inc.
Keywords
- Biologics
- Bone grafts
- Dental implants
- Regeneration
- Soft tissue grafts
- Tissue engineering
ASJC Scopus subject areas
- General Dentistry