Tissue Engineering: What is New?

Dolphus R. Dawson, Ahmed El-Ghannam, Joseph E. Van Sickels, Noel Ye Naung

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations


Soft and hard tissue engineering has expanded the frontiers of oral/maxillofacial augmentation. Soft tissue grafting enhancements include improving flap prevascularization and using stem cells and other cells to create not only the graft, but also the vascularization and soft tissue scaffolding for the graft. Hard tissue grafts have been enhanced by osteoinductive factors, such as bone morphogenic proteins, that have allowed the elimination of harvesting autogenous bone and thus decrease the need for other surgical sites. Advancements in bone graft scaffolds have developed via seeding with stem cells and improvement of the silica/calcium/phosphate composite to improve graft characteristics and healing.

Original languageEnglish
Pages (from-to)433-445
Number of pages13
JournalDental Clinics of North America
Issue number3
StatePublished - Jul 2019

Bibliographical note

Publisher Copyright:
© 2019 Elsevier Inc.


  • Biologics
  • Bone grafts
  • Dental implants
  • Regeneration
  • Soft tissue grafts
  • Tissue engineering

ASJC Scopus subject areas

  • General Dentistry


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