Abstract
Pulmonary hemorrhage after administration of tissue plasminogen activator (tPA) is a rare complication. We present a 15-year-old boy with a heterozygous pathogenic variant in ACTA2 who presented with right brachial artery aneurysm thrombosis treated initially with tPA, resulting in pulmonary hemorrhage. We hypothesize that the underlying pulmonary abnormalities caused by the pathogenic ACTA2 variant may be a risk factor for pulmonary hemorrhage after tPA administration.
Original language | English |
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Article number | 101558 |
Journal | Journal of Vascular Surgery Cases, Innovations and Techniques |
Volume | 10 |
Issue number | 6 |
DOIs | |
State | Published - Dec 2024 |
Bibliographical note
Publisher Copyright:© 2024 The Author(s)
Keywords
- ACTA2
- Brachial artery aneurysm
- Pulmonary hemorrhage
- Thrombosis
ASJC Scopus subject areas
- Surgery
- Cardiology and Cardiovascular Medicine