Toxicity and transcriptomic analysis in hyalella azteca suggests increased exposure and susceptibility of epibenthic organisms to zinc oxide nanoparticles

Helen C. Poynton, James M. Lazorchak, Christopher A. Impellitteri, Bonnie Blalock, Mark E. Smith, Katherine Struewing, Jason Unrine, Deborah Roose

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

Nanoparticles (NPs) are expected to make their way into the aquatic environment where sedimentation of particles will likely occur, putting benthic organisms at particular risk. Therefore, organisms such as Hyalella azteca, an epibenthic crustacean which forages at the sediment surface, is likely to have a high potential exposure. Here we show that zinc oxide (ZnO) NPs are more toxic to H. azteca compared with the corresponding metal ion, Zn2+. Dissolution of ZnO NPs contributes about 50% of the Zn measured in the ZnO NP suspensions, and cannot account for the toxicity of these particles to H. azteca. However, gene expression analysis is unable to distinguish between the ZnO NP exposures and zinc sulfate (ZnSO4) exposures at equitoxic concentrations. These results lead us to hypothesize that ZnO NPs provide an enhanced exposure route for Zn2+ uptake into H. azteca, and possibly other sediment dwelling organisms. Our study supports the prediction that sediment dwelling organisms are highly susceptible to the effects of ZnO NPs and should be considered in the risk assessment of these nanomaterials.

Original languageEnglish
Pages (from-to)9453-9460
Number of pages8
JournalEnvironmental Science and Technology
Volume47
Issue number16
DOIs
StatePublished - Aug 20 2013

ASJC Scopus subject areas

  • Chemistry (all)
  • Environmental Chemistry

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