Toxin-Induced Cerebellar Disorders

Katelyn Dolbec, Michael R. Dobbs, Mam Ibraheem

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

The cerebellum plays an important role in motor and nonmotor systems, with damage resulting in clinical manifestations presenting as weakness, ataxia, dysarthria, and nystagmus. There are numerous environmental and industrial agents as well as medications that, through either accidental or intentional use, can result in a range of neurologic presentations. The variability in the presentation is important to recognize promptly so that early cessation in exposure, use, or abuse can be initiated to reduce the severity of symptoms. Recognition of an agent causing the particular pathology is important so that the route of exposure, and subsequent treatment options can be identified.

Original languageEnglish
Pages (from-to)843-852
Number of pages10
JournalNeurologic Clinics
Volume38
Issue number4
DOIs
StatePublished - Nov 2020

Bibliographical note

Publisher Copyright:
© 2020 Elsevier Inc.

Keywords

  • Anticonvulsants
  • Ataxia
  • Cerebellum
  • Ethanol
  • Industrial exposure
  • Neurotoxicity
  • Nystagmus
  • Toxicology

ASJC Scopus subject areas

  • Clinical Neurology

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