@article{1db419b6345c4c7bb31e0a2cd4239db6,
title = "Transcranial optical monitoring of cerebrovascular hemodynamics in acute stroke patients",
abstract = "{"}Diffuse correlation spectroscopy{"} (DCS) is a technology for non-invasive transcranial measurement of cerebral blood flow (CBF) that can be hybridized with {"}near-infrared spectroscopy{"} (NIRS). Taken together these methods hold potential for monitoring hemodynamics in stroke patients. We explore the utility of DCS and NIRS to measure effects of head-of-bed (HOB) positioning at 30°, 15°, 0°, -5° and 0° angles in patients with acute ischemic stroke affecting frontal cortex and in controls. HOB positioning significantly altered CBF, oxy-hemoglobin (Hb02) and total-hemoglobin (THC) concentrations. Moreover, the presence of an ipsilateral infarct was a significant effect for all parameters. Results are consistent with the notion of impaired CBF autoregulation in the infarcted hemisphere.",
author = "Turgut Durduran and Chao Zhou and Edlow, \{Brian L.\} and Guoqiang Yu and Regine Choe and Kim, \{Meeri N.\} and Cucchiara, \{Brett L.\} and Putt, \{Mary E.\} and Qaisar Shah and Kasner, \{Scott E.\} and Greenberg, \{Joel H.\} and Yodh, \{Arjun G.\} and Detrey, \{John A.\}",
year = "2009",
month = mar,
day = "2",
doi = "10.1364/OE.17.003884",
language = "English",
volume = "17",
pages = "3884--3902",
number = "5",
}