TY - JOUR
T1 - Treatment of Persistent Postpartum Hellp Syndrome with Plasmapheresis
AU - Katz, Vern L.
AU - Watson, William J.
AU - Thorp, John M.
AU - Hansen, Wendy
AU - Bowes, Watson A.
PY - 1992/3
Y1 - 1992/3
N2 - Thrombocytopenia, associated with microangiopathic disease, is one characteristic of severe preeclampsia. Thrombocytopenia and intravascular hemolysis usually resolve by postpartum days 4 to 5. When thrombocytopenia secondary to microangiopathic disease persists, plasmapheresis may be used to arrest and reverse the process. Three patients over a 24-month period were successfully treated with plasma exchange with fresh frozen plasma. Several investigators who have cared for patients with persistent thrombocytopenia associated with preeclampsia have concluded that early plasmapheresis may be useful therapy. Plasma exchange should also be considered as a therapeutic option when clinical deterioration occurs due to microangiopathic disease.
AB - Thrombocytopenia, associated with microangiopathic disease, is one characteristic of severe preeclampsia. Thrombocytopenia and intravascular hemolysis usually resolve by postpartum days 4 to 5. When thrombocytopenia secondary to microangiopathic disease persists, plasmapheresis may be used to arrest and reverse the process. Three patients over a 24-month period were successfully treated with plasma exchange with fresh frozen plasma. Several investigators who have cared for patients with persistent thrombocytopenia associated with preeclampsia have concluded that early plasmapheresis may be useful therapy. Plasma exchange should also be considered as a therapeutic option when clinical deterioration occurs due to microangiopathic disease.
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U2 - 10.1055/s-2007-994683
DO - 10.1055/s-2007-994683
M3 - Article
C2 - 1590866
AN - SCOPUS:0026550703
SN - 0735-1631
VL - 9
SP - 120
EP - 122
JO - American Journal of Perinatology
JF - American Journal of Perinatology
IS - 2
ER -