Treatment of Persistent Postpartum Hellp Syndrome with Plasmapheresis

Vern L. Katz, William J. Watson, John M. Thorp, Wendy Hansen, Watson A. Bowes

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


Thrombocytopenia, associated with microangiopathic disease, is one characteristic of severe preeclampsia. Thrombocytopenia and intravascular hemolysis usually resolve by postpartum days 4 to 5. When thrombocytopenia secondary to microangiopathic disease persists, plasmapheresis may be used to arrest and reverse the process. Three patients over a 24-month period were successfully treated with plasma exchange with fresh frozen plasma. Several investigators who have cared for patients with persistent thrombocytopenia associated with preeclampsia have concluded that early plasmapheresis may be useful therapy. Plasma exchange should also be considered as a therapeutic option when clinical deterioration occurs due to microangiopathic disease.

Original languageEnglish
Pages (from-to)120-122
Number of pages3
JournalAmerican Journal of Perinatology
Issue number2
StatePublished - Mar 1992

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology


Dive into the research topics of 'Treatment of Persistent Postpartum Hellp Syndrome with Plasmapheresis'. Together they form a unique fingerprint.

Cite this