Trigeminal Traumatic Neuroma: a Comprehensive Review of the Literature Based On a Rare Case

Davis C. Thomas, Saranya Devatha Mallareddy, Jeffrey P. Okeson, Josna Thankachan, Priyanka Kodaganallur Pitchumani, Reshmy Chellam Pichammal

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Purpose of Review: Traumatic neuromas in general, and trigeminal traumatic neuromas in particular, are relatively rare entities originating from a damage to a corresponding nerve or its branches. This manuscript is a comprehensive review of the literature on trigeminal traumatic neuromas based on an interesting and challenging case of bilateral intraoral lesions. Recent Findings: The diagnosis for this patient was bilateral trigeminal traumatic neuromas. It is possible that these patients have a genetic predisposition to the development of these lesions. It is a neuropathic pain condition and may mimic dental and other trigeminal pain entities. Topical treatment with lidocaine gel, utilizing a custom-made neurosensory stent, rendered the patient significant and sustained pain relief. Summary: Trigeminal traumatic neuromas present a diagnostic challenge even to a seasoned clinician, due to the complex clinical features that may mimic other entities. Topical medications such as local anesthetics may be a good viable alternative to systemic medications to manage the pain associated with the condition. Early identification of the lesion and the associated pain helps in the succinct management of symptomatic trigeminal traumatic neuromas.

Original languageEnglish
Pages (from-to)219-233
Number of pages15
JournalCurrent Pain and Headache Reports
Issue number3
StatePublished - Mar 2022

Bibliographical note

Publisher Copyright:
© 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.


  • Neuropathic pain
  • Neurosensory stent
  • Oral
  • Tinel’s sign
  • Topical medication
  • Traumatic neuroma
  • Trigeminal nerve

ASJC Scopus subject areas

  • Clinical Neurology
  • Anesthesiology and Pain Medicine


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