TY - JOUR
T1 - Understanding the negative effects of depressive symptoms in patients with ESRD receiving hemodialysis.
AU - Khalil, Amani A.
AU - Lennie, Terry A.
AU - Frazier, Susan K.
PY - 2010/5
Y1 - 2010/5
N2 - Depressive symptoms are the most common psychological complication among patients with ESRD. Although depressive symptoms are a risk factor for increased morbidity and mortality, little is known about the mechanisms responsible for this association. Two pathways are described. The biological pathway involves interrelationships among depressive symptoms, inflammation, malnutrition, and atherosclerosis. The behavioral pathway includes the effects of depressive symptoms on dietary adherence. Recommendations include attention to therapeutic interventions that would influence these pathways to improve outcomes.
AB - Depressive symptoms are the most common psychological complication among patients with ESRD. Although depressive symptoms are a risk factor for increased morbidity and mortality, little is known about the mechanisms responsible for this association. Two pathways are described. The biological pathway involves interrelationships among depressive symptoms, inflammation, malnutrition, and atherosclerosis. The behavioral pathway includes the effects of depressive symptoms on dietary adherence. Recommendations include attention to therapeutic interventions that would influence these pathways to improve outcomes.
UR - http://www.scopus.com/inward/record.url?scp=77955974777&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77955974777&partnerID=8YFLogxK
M3 - Article
C2 - 20629466
AN - SCOPUS:77955974777
SN - 1526-744X
VL - 37
SP - 289-295, 308; quiz 296
JO - Nephrology nursing journal : journal of the American Nephrology Nurses' Association
JF - Nephrology nursing journal : journal of the American Nephrology Nurses' Association
IS - 3
ER -