United States critical illness and injury trials group

James M. Blum, Peter E. Morris, Greg S. Martin, Michelle N. Gong, Satish Bhagwanjee, Charles B. Cairns, J. Perren Cobb

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


The United States Critical Illness and Injury Trials (USCIIT) Group is an inclusive, grassroots "network of networks" with the dual missions of fostering investigator-initiated hypothesis testing and developing recommendations for strategic plans at a national level. The USCIIT Group's transformational approach enlists multidisciplinary investigative teams across institutions, critical illness and injury professional organizations, federal agencies that fund clinical and translational research, and industry partners. The USCIIT Group is endorsed by all major critical illness and injury professional organizations spanning the specialties of anesthesiology, emergency medicine, internal medicine, neurology, nursing, pediatrics, pharmacy and nutrition, surgery and trauma, and respiratory and physical therapy. Recent successes provide the opportunity to significantly increase the dialogue necessary to advance clinical and translational research on behalf of our community. More than 200 investigators are now involved across> 30 academic and community hospitals. Collectively, USCIIT Group investigators have enrolled > 10,000 patients from academic and community hospitals in studies during the last 3 years. To keep our readership "ahead of the curve," this article provides a vision for critical illness and injury research based on (1) programmatic organization of large-scale, multicentered collaborative studies and (2) annual strategic planning at a national scale across disciplines and stakeholders.

Original languageEnglish
Pages (from-to)808-813
Number of pages6
Issue number3
StatePublished - Mar 2013

Bibliographical note

Funding Information:
Funding/Support: This work was funded in part by the National Institutes of Health [Grants U13 GM083407, U01 HL108712] and the US Department of Health and Human Services [Contract HHSOl 0020 ll00062P].

Funding Information:
The United States Critical Illness and Injury Trials (USCIIT) Group created clinical research infrastructure to reduce the barriers to investigation for the critical illness and injury communities in the United States. 1 As an inclusive, grassroots “network of networks,” the USCIIT Group's dual missions are to foster investigator-initiated hypothesis testing and to develop recommendations for strategic plans at a national level. 2 The USCIIT Group was funded in 2008 by a National Institutes of Health (NIH) (National Institute of General Medical Science) meeting grant (U13) with four aims 3 :

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine


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