TY - JOUR
T1 - University-based outbreaks of meningococcal disease caused by serogroup B, United States, 2013-2018
AU - Soeters, Heidi M.
AU - McNamara, Lucy A.
AU - Blain, Amy E.
AU - Whaley, Melissa
AU - MacNeil, Jessica R.
AU - Hariri, Susan
AU - Mbaeyi, Sarah A.
AU - Harriman, Kathleen
AU - Winter, Kathleen
AU - Lett, Susan
AU - Becker, Ann
AU - Garvey, Kerry Beth
AU - Montana, Barbara
AU - Zaremski, Elizabeth F.
AU - Poissant, Tasha
AU - Lurie, Perrianne
AU - Negrón, Elizabeth A.
AU - Bandy, Utpala
AU - Ahrabi-Fard, Susann
N1 - Publisher Copyright:
© 2019, Centers for Disease Control and Prevention (CDC). All rights reserved.
PY - 2019/3
Y1 - 2019/3
N2 - We reviewed university-based outbreaks of meningococcal disease caused by serogroup B and vaccination responses in the United States in the years following serogroup B meningococcal (MenB) vaccine availability. Ten university-based outbreaks occurred in 7 states during 2013-2018, causing a total of 39 cases and 2 deaths. Outbreaks occurred at universities with 3,600-35,000 undergraduates. Outbreak case counts ranged from 2 to 9 cases; outbreak duration ranged from 0 to 376 days. All 10 universities implemented MenB vaccination: 3 primarily used MenB-FHbp and 7 used MenB-4C. Estimated first-dose vaccination coverage ranged from 14% to 98%. In 5 outbreaks, additional cases occurred 6-259 days following MenB vaccination initiation. Although it is difficult to predict outbreak trajectories and evaluate the effects of public health response measures, achieving high MenB vaccination coverage is crucial to help protect at-risk persons during outbreaks of meningococcal disease caused by this serogroup.
AB - We reviewed university-based outbreaks of meningococcal disease caused by serogroup B and vaccination responses in the United States in the years following serogroup B meningococcal (MenB) vaccine availability. Ten university-based outbreaks occurred in 7 states during 2013-2018, causing a total of 39 cases and 2 deaths. Outbreaks occurred at universities with 3,600-35,000 undergraduates. Outbreak case counts ranged from 2 to 9 cases; outbreak duration ranged from 0 to 376 days. All 10 universities implemented MenB vaccination: 3 primarily used MenB-FHbp and 7 used MenB-4C. Estimated first-dose vaccination coverage ranged from 14% to 98%. In 5 outbreaks, additional cases occurred 6-259 days following MenB vaccination initiation. Although it is difficult to predict outbreak trajectories and evaluate the effects of public health response measures, achieving high MenB vaccination coverage is crucial to help protect at-risk persons during outbreaks of meningococcal disease caused by this serogroup.
UR - http://www.scopus.com/inward/record.url?scp=85061997436&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85061997436&partnerID=8YFLogxK
U2 - 10.3201/eid2503.181574
DO - 10.3201/eid2503.181574
M3 - Article
C2 - 30789140
AN - SCOPUS:85061997436
SN - 1080-6040
VL - 25
SP - 434
EP - 440
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
IS - 3
ER -
