Urinary and serologic markers for interstitial cystitis: An update

David R. Wilkinson, Deborah R. Erickson

Research output: Contribution to journalReview articlepeer-review

20 Scopus citations


This update reviews the published literature from the past 2 years pertaining to urinary and serum markers for interstitial cystitis (IC). Literature on markers described before 2004 also is included when needed to provide background information for the current literature. The markers that have been the focus of the most research in the recent literature are antiproliferative factor, epidermal growth factor, heparin-binding epidermal growth factor-like growth factor, glycosaminoglycans, and bladder nitric oxide. These markers are discussed in consideration of their three different possible roles: 1) as diagnostic markers of IC; 2) distinguishing relevant subsets of IC patients; and 3) measuring disease activity and objectively following treatment response.

Original languageEnglish
Pages (from-to)414-422
Number of pages9
JournalCurrent Urology Reports
Issue number5
StatePublished - Sep 2006

ASJC Scopus subject areas

  • Urology


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