Urogenital Hypoplasia and X Chromosome Monosomy in a Draft Horse Filly

Kirsten Hahn; Theresa M. Conze; Bettina Wollanke; Ottmar Distl; Lutz S. Goehring; Tanja S. Witte

doi:10.1016/j.jevs.2020.103318

Urogenital Hypoplasia and X Chromosome Monosomy in a Draft Horse Filly

Kirsten Hahn, Theresa M. Conze, Bettina Wollanke, Ottmar Distl, Lutz S. Goehring, Tanja S. Witte

Veterinary Science

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

A 5-month-old draft horse filly was presented with incontinence and severe perivulvar dermatitis, which developed during the previous 2 months. Left-sided ectopic ureter entering in the caudal vaginal lumen, signs of cervix hypoplasia, and urine accumulation in the uterus were found during initial vaginal endoscopy. Therefore, a left ureter-nephrectomy was conducted under general anesthesia. Additionally, a cytogenetic examination was performed, which showed a XO monosomy with a 63,X/64,XX mosaic. This is the first case report presenting a chromosome abnormality in a draft horse filly combined with a left-sided ectopic ureter. Cytogenetic evaluation is recommended in any female horse with developmental abnormalities of the cervix, uterus, ovaries, or with irregularities of estrus.

Original language	English
Article number	103318
Journal	Journal of Equine Veterinary Science
Volume	96
DOIs	https://doi.org/10.1016/j.jevs.2020.103318
State	Published - Jan 2021

Bibliographical note

Publisher Copyright:
© 2020 Elsevier Inc.

Keywords

Ectopic ureter
Equine Turner syndrome
Monosomy X
Perivulvar dermatitis
Urinary incontinence

ASJC Scopus subject areas

Equine

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10.1016/j.jevs.2020.103318

Cite this

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title = "Urogenital Hypoplasia and X Chromosome Monosomy in a Draft Horse Filly",

abstract = "A 5-month-old draft horse filly was presented with incontinence and severe perivulvar dermatitis, which developed during the previous 2 months. Left-sided ectopic ureter entering in the caudal vaginal lumen, signs of cervix hypoplasia, and urine accumulation in the uterus were found during initial vaginal endoscopy. Therefore, a left ureter-nephrectomy was conducted under general anesthesia. Additionally, a cytogenetic examination was performed, which showed a XO monosomy with a 63,X/64,XX mosaic. This is the first case report presenting a chromosome abnormality in a draft horse filly combined with a left-sided ectopic ureter. Cytogenetic evaluation is recommended in any female horse with developmental abnormalities of the cervix, uterus, ovaries, or with irregularities of estrus.",

keywords = "Ectopic ureter, Equine Turner syndrome, Monosomy X, Perivulvar dermatitis, Urinary incontinence",

author = "Kirsten Hahn and Conze, {Theresa M.} and Bettina Wollanke and Ottmar Distl and Goehring, {Lutz S.} and Witte, {Tanja S.}",

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doi = "10.1016/j.jevs.2020.103318",

language = "English",

volume = "96",

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AU - Hahn, Kirsten

AU - Conze, Theresa M.

AU - Wollanke, Bettina

AU - Distl, Ottmar

AU - Goehring, Lutz S.

AU - Witte, Tanja S.

PY - 2021/1

Y1 - 2021/1

N2 - A 5-month-old draft horse filly was presented with incontinence and severe perivulvar dermatitis, which developed during the previous 2 months. Left-sided ectopic ureter entering in the caudal vaginal lumen, signs of cervix hypoplasia, and urine accumulation in the uterus were found during initial vaginal endoscopy. Therefore, a left ureter-nephrectomy was conducted under general anesthesia. Additionally, a cytogenetic examination was performed, which showed a XO monosomy with a 63,X/64,XX mosaic. This is the first case report presenting a chromosome abnormality in a draft horse filly combined with a left-sided ectopic ureter. Cytogenetic evaluation is recommended in any female horse with developmental abnormalities of the cervix, uterus, ovaries, or with irregularities of estrus.

AB - A 5-month-old draft horse filly was presented with incontinence and severe perivulvar dermatitis, which developed during the previous 2 months. Left-sided ectopic ureter entering in the caudal vaginal lumen, signs of cervix hypoplasia, and urine accumulation in the uterus were found during initial vaginal endoscopy. Therefore, a left ureter-nephrectomy was conducted under general anesthesia. Additionally, a cytogenetic examination was performed, which showed a XO monosomy with a 63,X/64,XX mosaic. This is the first case report presenting a chromosome abnormality in a draft horse filly combined with a left-sided ectopic ureter. Cytogenetic evaluation is recommended in any female horse with developmental abnormalities of the cervix, uterus, ovaries, or with irregularities of estrus.

KW - Ectopic ureter

KW - Equine Turner syndrome

KW - Monosomy X

KW - Perivulvar dermatitis

KW - Urinary incontinence

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ER -

Urogenital Hypoplasia and X Chromosome Monosomy in a Draft Horse Filly

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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