Abstract
Pediatric genitourinary tumors exhibit unique genetic alterations, pathogenesis, and prognosis which requires tailored treatment strategies distinct from those of adult tumors. This chapter identifies approaches to the diagnosis, staging, treatment, and surveillance of common pediatric renal, testis and bladder tumors and genitourinary rhabdomyosarcoma. Treatment approaches discussed in this chapter focus on evidence-based guidelines based on cooperative group studies which have been fundamental to improved clinical outcomes. Additionally, common late effects associated with aggressive treatment modalities contributing to considerable comorbidity will be discussed.
Original language | English |
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Title of host publication | Practical Pediatric Urology |
Subtitle of host publication | An Evidence-Based Approach |
Pages | 405-431 |
Number of pages | 27 |
ISBN (Electronic) | 9783030540203 |
DOIs | |
State | Published - Dec 17 2020 |
Bibliographical note
Publisher Copyright:© Springer Nature Switzerland AG 2021.
Keywords
- Germ cell tumor
- Gonadal stromal tumor
- Renal cell carcinoma
- Rhabdomyosarcoma
- Teratoma
- Urothelial cell carcinoma
- Wilms tumor
- Yolk sac tumor
ASJC Scopus subject areas
- General Medicine