Abstract
The use of fluorogenic substrates to measure enzymatic activity is widely used to understand function within different experimental models. ACE2 is important in understanding the balance between AngII and Ang-(1-7) and how this balance could then in turn influence hypertension or other disease outcomes. Here, we describe a method to measure ACE2 activity in abdominal aorta of hyperlipidemic mice under both saline and AngII infusion.
Original language | English |
---|---|
Title of host publication | Methods in Molecular Biology |
Pages | 61-67 |
Number of pages | 7 |
DOIs | |
State | Published - 2017 |
Publication series
Name | Methods in Molecular Biology |
---|---|
Volume | 1614 |
ISSN (Print) | 1064-3745 |
Bibliographical note
Publisher Copyright:© 2017, Springer Science+Business Media LLC.
Keywords
- Activity
- Angiotensin converting enzyme 2
- Aorta
- Enzyme
- Fluorescence
ASJC Scopus subject areas
- Molecular Biology
- Genetics