The use of fluorogenic substrates to measure enzymatic activity is widely used to understand function within different experimental models. ACE2 is important in understanding the balance between AngII and Ang-(1-7) and how this balance could then in turn influence hypertension or other disease outcomes. Here, we describe a method to measure ACE2 activity in abdominal aorta of hyperlipidemic mice under both saline and AngII infusion.
|Title of host publication||Methods in Molecular Biology|
|Number of pages||7|
|State||Published - 2017|
|Name||Methods in Molecular Biology|
Bibliographical notePublisher Copyright:
© 2017, Springer Science+Business Media LLC.
- Angiotensin converting enzyme 2
ASJC Scopus subject areas
- Molecular Biology