Utility of point-of-care vs reference laboratory testing for the evaluation of glucose levels

O. M. Andriankaja, F. J. Muñoz-Torres, J. L. Vergara, C. M. Pérez, K. Joshipura

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Aims: To assess the level of agreement between point-of-care and laboratory reference glucose values in defining glycaemic status. Methods: We analysed 1292 overweight/obese, non-institutionalized participants, aged 40–65 years, in the San Juan Overweight Adults Longitudinal Study. Fasting venous blood glucose was determined using a point-of-care Bayer Contour Blood Glucose Meter and by Vitros System 250 instrument (laboratory). American Diabetes Association thresholds were used to classify participants into normoglycaemia (< 5.6 mmol/l), prediabetes (5.6 to 6.9 mmol/l), or diabetes groups (≥ 7 mmol/l). Results: Bland–Altman plot analysis showed a slope of 0.04 (P=0.002) for the regression between the mean difference and the average of the two methods. The slopes were significantly different from zero among people with normoglycaemia (β=–0.57, P<0.001), and prediabetes (β=–0.75, P<0.001) but not among people with diabetes (β=–0.02, P=0.68). When the prediabetes and diabetes groups were merged into one group, the slope was 0.01, and the glucose values remained similar using the two methods (P=0.76). Conclusion: Point-of-care blood glucose measurement may be useful to screen people with diabetes, and to assess glucose among individuals with diabetes where blood can be drawn, but laboratory tests are unavailable or untimely.

Original languageEnglish
Pages (from-to)626-632
Number of pages7
JournalDiabetic Medicine
Volume36
Issue number5
DOIs
StatePublished - May 2019

Bibliographical note

Funding Information:
This work was fully supported by Award Number R01DE020111 from the National Institute of Dental and Craniofacial Research (NIDCR) and partially supported by award number 2U54MD007587 from the National Institute on Minority Health and Health Disparities, award number 1U54RR026139-01A1 from the National Center for Research Resources, and award Number K23 DE025313-03 from the NIDCR.

Publisher Copyright:
© 2019 Diabetes UK

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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