Validamycin reduces the transmission of Tomato chlorotic virus by Bemisia tabaci

Yang Mu; Xiaobin Shi; Zhuo Zhang; Zhanhong Zhang; Tianqi Wang; Yanqi Wang; Yan Wei; Xuguo Zhou; Min Xiang; Yong Liu; Deyong Zhang

doi:10.1007/s10340-021-01449-1

Validamycin reduces the transmission of Tomato chlorotic virus by Bemisia tabaci

Yang Mu, Xiaobin Shi, Zhuo Zhang, Zhanhong Zhang, Tianqi Wang, Yanqi Wang, Yan Wei, Xuguo Zhou, Min Xiang, Yong Liu, Deyong Zhang

Entomology

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Bemisia tabaci (Gennadius), commonly known as whitefly or sweet potato whitefly, causes feeding-related injuries to plants, and transmits more than 200 different plant viruses, including Tomato chlorosis virus (ToCV). Control of B. tabaci is therefore one of the key measures in the comprehensive prevention and control of ToCV outbreak in tomato fields. Many insects rely on the hydrolysis of trehalose, broken down by the enzyme trehalase, to power their flight and other life-sustaining activities. B. tabaci encodes just one trehalase, making it an attractive target. In this study, the mechanism underlying the involvement of trehalase in the transmission of ToCV by B. tabaci was investigated. Also, the effect of the trehalase inhibitor, validamycin, on ToCV transmission was assessed. Our results showed that trehalase activity was upregulated in B. tabaci fed on ToCV-infected tomato plants. Treating B. tabaci with validamycin decreased the trehalase activity, and significantly reduced its transmission of ToCV. Validamycin treatment also inhibited the flight and feeding ability of B. tabaci. These results indicate that proper function of trehalase is required by whitefly to transmit ToCV with high efficiency. These provides an important theoretical basis for targeting whitefly trehalase as one way to control ToCV transmission.

Original language	English
Pages (from-to)	1261-1272
Number of pages	12
Journal	Journal of Pest Science
Volume	95
Issue number	3
DOIs	https://doi.org/10.1007/s10340-021-01449-1
State	Published - Jun 2022

Bibliographical note

Funding Information:
This work was supported by the Agriculture Research System of China (No. CARS-16-E-17, and CARS-23-D-02), the Hunan Natural Science Foundation (No. 2019JJ30014), and the National Natural Science Foundation of China (Nos. 32030088, 32072383, 31872932, 31901854).

Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Keywords

Bemisia tabaci
Tomato chlorotic virus (ToCV)
Trehalase
Trehalose
Validamycin

ASJC Scopus subject areas

Ecology, Evolution, Behavior and Systematics
Ecology
Agronomy and Crop Science
Plant Science
Insect Science

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10.1007/s10340-021-01449-1

Cite this

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title = "Validamycin reduces the transmission of Tomato chlorotic virus by Bemisia tabaci",

abstract = "Bemisia tabaci (Gennadius), commonly known as whitefly or sweet potato whitefly, causes feeding-related injuries to plants, and transmits more than 200 different plant viruses, including Tomato chlorosis virus (ToCV). Control of B. tabaci is therefore one of the key measures in the comprehensive prevention and control of ToCV outbreak in tomato fields. Many insects rely on the hydrolysis of trehalose, broken down by the enzyme trehalase, to power their flight and other life-sustaining activities. B. tabaci encodes just one trehalase, making it an attractive target. In this study, the mechanism underlying the involvement of trehalase in the transmission of ToCV by B. tabaci was investigated. Also, the effect of the trehalase inhibitor, validamycin, on ToCV transmission was assessed. Our results showed that trehalase activity was upregulated in B. tabaci fed on ToCV-infected tomato plants. Treating B. tabaci with validamycin decreased the trehalase activity, and significantly reduced its transmission of ToCV. Validamycin treatment also inhibited the flight and feeding ability of B. tabaci. These results indicate that proper function of trehalase is required by whitefly to transmit ToCV with high efficiency. These provides an important theoretical basis for targeting whitefly trehalase as one way to control ToCV transmission.",

keywords = "Bemisia tabaci, Tomato chlorotic virus (ToCV), Trehalase, Trehalose, Validamycin",

author = "Yang Mu and Xiaobin Shi and Zhuo Zhang and Zhanhong Zhang and Tianqi Wang and Yanqi Wang and Yan Wei and Xuguo Zhou and Min Xiang and Yong Liu and Deyong Zhang",

note = "Funding Information: This work was supported by the Agriculture Research System of China (No. CARS-16-E-17, and CARS-23-D-02), the Hunan Natural Science Foundation (No. 2019JJ30014), and the National Natural Science Foundation of China (Nos. 32030088, 32072383, 31872932, 31901854). Publisher Copyright: {\textcopyright} 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.",

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AU - Mu, Yang

AU - Shi, Xiaobin

AU - Zhang, Zhuo

AU - Zhang, Zhanhong

AU - Wang, Tianqi

AU - Wang, Yanqi

AU - Wei, Yan

AU - Zhou, Xuguo

AU - Xiang, Min

AU - Liu, Yong

AU - Zhang, Deyong

N1 - Funding Information: This work was supported by the Agriculture Research System of China (No. CARS-16-E-17, and CARS-23-D-02), the Hunan Natural Science Foundation (No. 2019JJ30014), and the National Natural Science Foundation of China (Nos. 32030088, 32072383, 31872932, 31901854). Publisher Copyright: © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

PY - 2022/6

Y1 - 2022/6

N2 - Bemisia tabaci (Gennadius), commonly known as whitefly or sweet potato whitefly, causes feeding-related injuries to plants, and transmits more than 200 different plant viruses, including Tomato chlorosis virus (ToCV). Control of B. tabaci is therefore one of the key measures in the comprehensive prevention and control of ToCV outbreak in tomato fields. Many insects rely on the hydrolysis of trehalose, broken down by the enzyme trehalase, to power their flight and other life-sustaining activities. B. tabaci encodes just one trehalase, making it an attractive target. In this study, the mechanism underlying the involvement of trehalase in the transmission of ToCV by B. tabaci was investigated. Also, the effect of the trehalase inhibitor, validamycin, on ToCV transmission was assessed. Our results showed that trehalase activity was upregulated in B. tabaci fed on ToCV-infected tomato plants. Treating B. tabaci with validamycin decreased the trehalase activity, and significantly reduced its transmission of ToCV. Validamycin treatment also inhibited the flight and feeding ability of B. tabaci. These results indicate that proper function of trehalase is required by whitefly to transmit ToCV with high efficiency. These provides an important theoretical basis for targeting whitefly trehalase as one way to control ToCV transmission.

AB - Bemisia tabaci (Gennadius), commonly known as whitefly or sweet potato whitefly, causes feeding-related injuries to plants, and transmits more than 200 different plant viruses, including Tomato chlorosis virus (ToCV). Control of B. tabaci is therefore one of the key measures in the comprehensive prevention and control of ToCV outbreak in tomato fields. Many insects rely on the hydrolysis of trehalose, broken down by the enzyme trehalase, to power their flight and other life-sustaining activities. B. tabaci encodes just one trehalase, making it an attractive target. In this study, the mechanism underlying the involvement of trehalase in the transmission of ToCV by B. tabaci was investigated. Also, the effect of the trehalase inhibitor, validamycin, on ToCV transmission was assessed. Our results showed that trehalase activity was upregulated in B. tabaci fed on ToCV-infected tomato plants. Treating B. tabaci with validamycin decreased the trehalase activity, and significantly reduced its transmission of ToCV. Validamycin treatment also inhibited the flight and feeding ability of B. tabaci. These results indicate that proper function of trehalase is required by whitefly to transmit ToCV with high efficiency. These provides an important theoretical basis for targeting whitefly trehalase as one way to control ToCV transmission.

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Validamycin reduces the transmission of Tomato chlorotic virus by Bemisia tabaci

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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