Validated LC-MS/MS method for simultaneous determination of SIM and its acid form in human plasma and cell lysate: Pharmacokinetic application

Biochemistry, Genetics and Molecular Biology

• Antineoplastic Activity 9%
• Cell Lysate 100%
• Coenzyme A 9%
• Drug Megadose 27%
• Hyperlipidemia 18%
• Ionization 9%
• Liquid Chromatography Mass Spectrometry 100%
• Peripheral Blood Mononuclear Cell 18%
• pH 9%
• Pharmacokinetics 100%
• Plasma Cell 9%
• Reductase 9%
• Sample 9%
• Simvastatin 100%
• Solution and Solubility 9%
• Tandem Mass Spectrometry 100%
• Triple Quadrupole Mass Spectrometer 9%

Chemistry

• Acetonitrile 9%
• Acid 100%
• Ammonium Acetate 9%
• Analytes 9%
• Application 100%
• Aqueous Solution 9%
• Assay 9%
• Coenzyme A 9%
• Dose 27%
• Inhibitor 9%
• Ion 9%
• Ionization 9%
• Pharmacokinetics 100%
• Quadrupole 9%
• Sample 9%
• Simvastatin 100%
• Spray 9%
• Tandem Mass Spectrometry 100%

Chemical Engineering

• Acetonitrile 50%
• Acid 100%
• Mobile Phase Composition 50%