Abstract
Calf blood flow was measured simultaneously in healthy human subjects (n = 7) during cuff inflation and deflation using near-infrared diffuse correlation spectroscopy (DCS) and arterial spin labeled perfusion MRI (ASL-MRI). The DCS and ASL-MRI data exhibited highly correlated absolute and relative dynamic flow responses in each individual (p < 0.001). Peak flow variations during hyperemia were also significantly correlated, though more for relative (p = 0.003) than absolute (p = 0.016) flow. Repeated measurement variation was less than 8% for both modalities. The results provide much needed quantitative blood flow validation of the diffuse optical correlation method in humans.
Original language | English |
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Pages (from-to) | 1064-1075 |
Number of pages | 12 |
Journal | Optics Express |
Volume | 15 |
Issue number | 3 |
DOIs | |
State | Published - Feb 5 2007 |
Bibliographical note
Copyright:Copyright 2014 Elsevier B.V., All rights reserved.
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics