TY - JOUR
T1 - Variability in B-mode ultrasound measurements in the Atherosclerosis Risk in Communities (ARIC) study
AU - Chambless, Lloyd E.
AU - Zhong, Ming M.
AU - Arnett, Donna
AU - Folsom, Aaron R.
AU - Riley, Ward A.
AU - Heiss, Gerardo
PY - 1996
Y1 - 1996
N2 - The Atherosclerosis Risk in Communities (ARIC) study is n multicenter, long-term epidemiologic study that uses B-mode ultrasound primarily to measure carotid arterial intima-media wall thickness. To assess the reliability of the measurement process of this application of B-mode technology to population-based research, 36 volunteers from four centers were scanned at three visits, 7-14 days apart. Estimates of the components of variation in the B-mode measurements of artery wall thickness from between- person, between-sonographer, within-sonographer, between-reader and within- reader variation are presented, along with estimates of the correlation R between measures made at repeat visits by different sonographers and read by different readers. The estimates of R for mean intima-media thickness are 0.69, 0.60, 0.54 and 0.66 for the carotid bifurcation, internal carotid, common carotid, and three-segment overall carotid mean, respectively. When these are adjusted to account for differences in between-person variance between the ancillary study and the main ARIC study, the estimated site- specific reliability coefficients appropriate to the ARIC study population are 0.77, 0.73 and 0.70 for mean carotid far-wall intima-media thickness at the carotid bifurcation and the internal and common carotid arteries.
AB - The Atherosclerosis Risk in Communities (ARIC) study is n multicenter, long-term epidemiologic study that uses B-mode ultrasound primarily to measure carotid arterial intima-media wall thickness. To assess the reliability of the measurement process of this application of B-mode technology to population-based research, 36 volunteers from four centers were scanned at three visits, 7-14 days apart. Estimates of the components of variation in the B-mode measurements of artery wall thickness from between- person, between-sonographer, within-sonographer, between-reader and within- reader variation are presented, along with estimates of the correlation R between measures made at repeat visits by different sonographers and read by different readers. The estimates of R for mean intima-media thickness are 0.69, 0.60, 0.54 and 0.66 for the carotid bifurcation, internal carotid, common carotid, and three-segment overall carotid mean, respectively. When these are adjusted to account for differences in between-person variance between the ancillary study and the main ARIC study, the estimated site- specific reliability coefficients appropriate to the ARIC study population are 0.77, 0.73 and 0.70 for mean carotid far-wall intima-media thickness at the carotid bifurcation and the internal and common carotid arteries.
KW - B-mode ultrasound
KW - Measurement variation
KW - Quantitative imaging
KW - Reliability
KW - Repeatability
KW - Variance
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U2 - 10.1016/0301-5629(96)00039-7
DO - 10.1016/0301-5629(96)00039-7
M3 - Article
C2 - 8865551
AN - SCOPUS:0029900106
SN - 0301-5629
VL - 22
SP - 545
EP - 554
JO - Ultrasound in Medicine and Biology
JF - Ultrasound in Medicine and Biology
IS - 5
ER -