Variables associated with familial suicide attempts in a sample of suicide attempters

Enrique Baca-Garcia, M. Mercedes Perez-Rodriguez, Dolores Saiz-Gonzalez, Ignacio Basurte-Villamor, Jeronimo Saiz-Ruiz, José M. Leiva-Murillo, Mario de Prado-Cumplido, Ricardo Santiago-Mozos, Antonio Artés-Rodríguez, Jose de Leon

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Attempted suicide appears to be a familial behavior. This study aims to determine the variables associated with family history of attempted suicide in a large sample of suicide attempters. The sample included 539 suicide attempters 18 years or older recruited in an emergency room. The two dichotomous dependent variables were family history of suicide attempt (10%, 51/539) and of completed suicide (4%, 23/539). Independent variables were 101 clinical variables studied with two data mining techniques: Random Forest and Forward Selection. A model for family history of completed suicide could not be developed. A classificatory model for family history of attempted suicide included the use of alcohol in the intent and family history of completed suicide (sensitivity, specificity, 98.7%; and accuracy, 96.6%). This is the first study that uses a powerful new statistical methodology, data mining, in the field of familial suicidal behaviors and suggests that it may be important to study familial variables associated with alcohol use to better understand the familiality of suicide attempts.

Original languageEnglish
Pages (from-to)1312-1316
Number of pages5
JournalProgress in Neuro-Psychopharmacology and Biological Psychiatry
Issue number6
StatePublished - Aug 15 2007

Bibliographical note

Funding Information:
This study was conducted at the Hospital Ramon y Cajal, Madrid, Spain, and recruitment was supported by a National Alliance for Research on Schizophrenia and Affective Disorders (NARSAD) Young Investigator Award to Dr. Baca-Garcia and a grant from the Spanish Health Ministry (FIS 01/0077-01), Harriet and Esteban Vicente Foundation and Conchita Rabago Foundation. Dr. Baca-Garcia is the Lilly Suicide Scholar at Columbia University. The statistical analyses described in this article were conducted without external support. The authors thank Lorraine Maw, M.A., for editorial assistance.


  • Alcohol drinking
  • Alcohol-related disorders
  • Attempted suicide
  • Genetics
  • Suicide

ASJC Scopus subject areas

  • Pharmacology
  • Biological Psychiatry


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