Variables associated with familial suicide attempts in a sample of suicide attempters

Enrique Baca-Garcia; M. Mercedes Perez-Rodriguez; Dolores Saiz-Gonzalez; Ignacio Basurte-Villamor; Jeronimo Saiz-Ruiz; José M. Leiva-Murillo; Mario de Prado-Cumplido; Ricardo Santiago-Mozos; Antonio Artés-Rodríguez; Jose de Leon

doi:10.1016/j.pnpbp.2007.05.019

Variables associated with familial suicide attempts in a sample of suicide attempters

Enrique Baca-Garcia, M. Mercedes Perez-Rodriguez, Dolores Saiz-Gonzalez, Ignacio Basurte-Villamor, Jeronimo Saiz-Ruiz, José M. Leiva-Murillo, Mario de Prado-Cumplido, Ricardo Santiago-Mozos, Antonio Artés-Rodríguez, Jose de Leon

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

Attempted suicide appears to be a familial behavior. This study aims to determine the variables associated with family history of attempted suicide in a large sample of suicide attempters. The sample included 539 suicide attempters 18 years or older recruited in an emergency room. The two dichotomous dependent variables were family history of suicide attempt (10%, 51/539) and of completed suicide (4%, 23/539). Independent variables were 101 clinical variables studied with two data mining techniques: Random Forest and Forward Selection. A model for family history of completed suicide could not be developed. A classificatory model for family history of attempted suicide included the use of alcohol in the intent and family history of completed suicide (sensitivity, specificity, 98.7%; and accuracy, 96.6%). This is the first study that uses a powerful new statistical methodology, data mining, in the field of familial suicidal behaviors and suggests that it may be important to study familial variables associated with alcohol use to better understand the familiality of suicide attempts.

Original language	English
Pages (from-to)	1312-1316
Number of pages	5
Journal	Progress in Neuro-Psychopharmacology and Biological Psychiatry
Volume	31
Issue number	6
DOIs	https://doi.org/10.1016/j.pnpbp.2007.05.019
State	Published - Aug 15 2007

Bibliographical note

Funding Information:
This study was conducted at the Hospital Ramon y Cajal, Madrid, Spain, and recruitment was supported by a National Alliance for Research on Schizophrenia and Affective Disorders (NARSAD) Young Investigator Award to Dr. Baca-Garcia and a grant from the Spanish Health Ministry (FIS 01/0077-01), Harriet and Esteban Vicente Foundation and Conchita Rabago Foundation. Dr. Baca-Garcia is the Lilly Suicide Scholar at Columbia University. The statistical analyses described in this article were conducted without external support. The authors thank Lorraine Maw, M.A., for editorial assistance.

Funding

This study was conducted at the Hospital Ramon y Cajal, Madrid, Spain, and recruitment was supported by a National Alliance for Research on Schizophrenia and Affective Disorders (NARSAD) Young Investigator Award to Dr. Baca-Garcia and a grant from the Spanish Health Ministry (FIS 01/0077-01), Harriet and Esteban Vicente Foundation and Conchita Rabago Foundation. Dr. Baca-Garcia is the Lilly Suicide Scholar at Columbia University. The statistical analyses described in this article were conducted without external support. The authors thank Lorraine Maw, M.A., for editorial assistance.

Funders	Funder number
Harriet and Esteban Vicente Foundation
National Alliance for Research on Schizophrenia and Affective Disorders
Spanish Ministry of Health	FIS 01/0077-01
Fundación Conchita Rábago

Keywords

Alcohol drinking
Alcohol-related disorders
Attempted suicide
Genetics
Suicide

ASJC Scopus subject areas

Pharmacology
Biological Psychiatry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.pnpbp.2007.05.019

Cite this

Baca-Garcia, E., Perez-Rodriguez, M. M., Saiz-Gonzalez, D., Basurte-Villamor, I., Saiz-Ruiz, J., Leiva-Murillo, J. M., de Prado-Cumplido, M., Santiago-Mozos, R., Artés-Rodríguez, A., & de Leon, J. (2007). Variables associated with familial suicide attempts in a sample of suicide attempters. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 31(6), 1312-1316. https://doi.org/10.1016/j.pnpbp.2007.05.019

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title = "Variables associated with familial suicide attempts in a sample of suicide attempters",

abstract = "Attempted suicide appears to be a familial behavior. This study aims to determine the variables associated with family history of attempted suicide in a large sample of suicide attempters. The sample included 539 suicide attempters 18 years or older recruited in an emergency room. The two dichotomous dependent variables were family history of suicide attempt (10%, 51/539) and of completed suicide (4%, 23/539). Independent variables were 101 clinical variables studied with two data mining techniques: Random Forest and Forward Selection. A model for family history of completed suicide could not be developed. A classificatory model for family history of attempted suicide included the use of alcohol in the intent and family history of completed suicide (sensitivity, specificity, 98.7%; and accuracy, 96.6%). This is the first study that uses a powerful new statistical methodology, data mining, in the field of familial suicidal behaviors and suggests that it may be important to study familial variables associated with alcohol use to better understand the familiality of suicide attempts.",

keywords = "Alcohol drinking, Alcohol-related disorders, Attempted suicide, Genetics, Suicide",

author = "Enrique Baca-Garcia and Perez-Rodriguez, {M. Mercedes} and Dolores Saiz-Gonzalez and Ignacio Basurte-Villamor and Jeronimo Saiz-Ruiz and Leiva-Murillo, {Jos{\'e} M.} and {de Prado-Cumplido}, Mario and Ricardo Santiago-Mozos and Antonio Art{\'e}s-Rodr{\'i}guez and {de Leon}, Jose",

note = "Funding Information: This study was conducted at the Hospital Ramon y Cajal, Madrid, Spain, and recruitment was supported by a National Alliance for Research on Schizophrenia and Affective Disorders (NARSAD) Young Investigator Award to Dr. Baca-Garcia and a grant from the Spanish Health Ministry (FIS 01/0077-01), Harriet and Esteban Vicente Foundation and Conchita Rabago Foundation. Dr. Baca-Garcia is the Lilly Suicide Scholar at Columbia University. The statistical analyses described in this article were conducted without external support. The authors thank Lorraine Maw, M.A., for editorial assistance.",

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Baca-Garcia, E, Perez-Rodriguez, MM, Saiz-Gonzalez, D, Basurte-Villamor, I, Saiz-Ruiz, J, Leiva-Murillo, JM, de Prado-Cumplido, M, Santiago-Mozos, R, Artés-Rodríguez, A & de Leon, J 2007, 'Variables associated with familial suicide attempts in a sample of suicide attempters', Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 31, no. 6, pp. 1312-1316. https://doi.org/10.1016/j.pnpbp.2007.05.019

TY - JOUR

T1 - Variables associated with familial suicide attempts in a sample of suicide attempters

AU - Baca-Garcia, Enrique

AU - Perez-Rodriguez, M. Mercedes

AU - Saiz-Gonzalez, Dolores

AU - Basurte-Villamor, Ignacio

AU - Saiz-Ruiz, Jeronimo

AU - Leiva-Murillo, José M.

AU - de Prado-Cumplido, Mario

AU - Santiago-Mozos, Ricardo

AU - Artés-Rodríguez, Antonio

AU - de Leon, Jose

N1 - Funding Information: This study was conducted at the Hospital Ramon y Cajal, Madrid, Spain, and recruitment was supported by a National Alliance for Research on Schizophrenia and Affective Disorders (NARSAD) Young Investigator Award to Dr. Baca-Garcia and a grant from the Spanish Health Ministry (FIS 01/0077-01), Harriet and Esteban Vicente Foundation and Conchita Rabago Foundation. Dr. Baca-Garcia is the Lilly Suicide Scholar at Columbia University. The statistical analyses described in this article were conducted without external support. The authors thank Lorraine Maw, M.A., for editorial assistance.

PY - 2007/8/15

Y1 - 2007/8/15

N2 - Attempted suicide appears to be a familial behavior. This study aims to determine the variables associated with family history of attempted suicide in a large sample of suicide attempters. The sample included 539 suicide attempters 18 years or older recruited in an emergency room. The two dichotomous dependent variables were family history of suicide attempt (10%, 51/539) and of completed suicide (4%, 23/539). Independent variables were 101 clinical variables studied with two data mining techniques: Random Forest and Forward Selection. A model for family history of completed suicide could not be developed. A classificatory model for family history of attempted suicide included the use of alcohol in the intent and family history of completed suicide (sensitivity, specificity, 98.7%; and accuracy, 96.6%). This is the first study that uses a powerful new statistical methodology, data mining, in the field of familial suicidal behaviors and suggests that it may be important to study familial variables associated with alcohol use to better understand the familiality of suicide attempts.

AB - Attempted suicide appears to be a familial behavior. This study aims to determine the variables associated with family history of attempted suicide in a large sample of suicide attempters. The sample included 539 suicide attempters 18 years or older recruited in an emergency room. The two dichotomous dependent variables were family history of suicide attempt (10%, 51/539) and of completed suicide (4%, 23/539). Independent variables were 101 clinical variables studied with two data mining techniques: Random Forest and Forward Selection. A model for family history of completed suicide could not be developed. A classificatory model for family history of attempted suicide included the use of alcohol in the intent and family history of completed suicide (sensitivity, specificity, 98.7%; and accuracy, 96.6%). This is the first study that uses a powerful new statistical methodology, data mining, in the field of familial suicidal behaviors and suggests that it may be important to study familial variables associated with alcohol use to better understand the familiality of suicide attempts.

KW - Alcohol drinking

KW - Alcohol-related disorders

KW - Attempted suicide

KW - Genetics

KW - Suicide

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U2 - 10.1016/j.pnpbp.2007.05.019

DO - 10.1016/j.pnpbp.2007.05.019

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C2 - 17614183

AN - SCOPUS:34447548911

SN - 0278-5846

VL - 31

SP - 1312

EP - 1316

JO - Progress in Neuro-Psychopharmacology and Biological Psychiatry

JF - Progress in Neuro-Psychopharmacology and Biological Psychiatry

IS - 6

ER -

Variables associated with familial suicide attempts in a sample of suicide attempters

Abstract

Bibliographical note

Funding

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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Cite this