Vascular contributions to cognitive impairment and dementia including Alzheimer's disease

Heather M. Snyder, Roderick A. Corriveau, Suzanne Craft, James E. Faber, Steven M. Greenberg, David Knopman, Bruce T. Lamb, Thomas J. Montine, Maiken Nedergaard, Chris B. Schaffer, Julie A. Schneider, Cheryl Wellington, Donna M. Wilcock, Gregory J. Zipfel, Berislav Zlokovic, Lisa J. Bain, Francesca Bosetti, Zorina S. Galis, Walter Koroshetz, Maria C. Carrillo

Research output: Contribution to journalReview articlepeer-review

450 Scopus citations

Abstract

Scientific evidence continues to demonstrate the linkage of vascular contributions to cognitive impairment and dementia such as Alzheimer's disease. In December, 2013, the Alzheimer's Association, with scientific input from the National Institute of Neurological Disorders and Stroke and the National Heart, Lung and Blood Institute from the National Institutes of Health, convened scientific experts to discuss the research gaps in our understanding of how vascular factors contribute to Alzheimer's disease and related dementia. This manuscript summarizes the meeting and the resultant discussion, including an outline of next steps needed to move this area of research forward.

Original languageEnglish
Pages (from-to)710-717
Number of pages8
JournalAlzheimer's and Dementia
Volume11
Issue number6
DOIs
StatePublished - Jun 1 2015

Bibliographical note

Publisher Copyright:
© 2015 The Alzheimer's Association. Published by Elsevier Inc. All rights reserved.

Keywords

  • Alzheimer's disease
  • Animal models
  • Biomarkers
  • Dementia
  • Small vessel disease
  • Vascular dementia

ASJC Scopus subject areas

  • Clinical Neurology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health
  • Cellular and Molecular Neuroscience
  • Health Policy
  • Developmental Neuroscience
  • Epidemiology

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