Venous thromboembolism during pregnancy and postpartum period: an updated review

Sanaullah Mojaddedi, Javairia Jamil, Andrew Abraham, Dawood Jamil, Hend Mansoor, Islam Y. Elgendy

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Venous thromboembolism (VTE) is a leading cause of maternal mortality. The risk of VTE in pregnant and postpartum women is ~ five times higher compared with non-pregnant women. There is a physiological tendency to a hypercoagulable state, from conception to the postpartum period. Several non-obstetric risk factors independently increase the risk of VTE. Since most signs and symptoms of VTE might mimic those of a normal pregnancy, a high index of suspicion is warranted to establish the diagnosis. D-dimer, ultrasonography and computed tomography pulmonary angiography are the primary tools for VTE diagnosis. Management mainly revolves around systemic anticoagulation with heparin. Advanced therapy options exist, but these can be considered for selected high-risk cases.

Original languageEnglish
Pages (from-to)62-74
Number of pages13
JournalMinerva Medica
Volume116
Issue number1
DOIs
StatePublished - Feb 2025

Bibliographical note

Publisher Copyright:
© 2024 EDIZIONI MINERVA MEDICA.

Keywords

  • Postpartum period
  • Pregnancy
  • Pulmonary embolism
  • Venous thromboembolism

ASJC Scopus subject areas

  • General Medicine

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