Abstract
This paper constructed a prototype laser cytometer that has the potential to rapidly probe individual cells in large populations. The cytometer is based on a biological microcavity laser technique that employs a vertical-cavity surface-emitting semiconductor to provide gain for light confined by cells. This laser technique has critical advantages over conventional fluorescence detection methods. The microcavity laser provides intense, monochromatic, narrow divergence light signals that are emitted from lasing modes confined by the cell. This cytometer is used in two basic configurations. First, as a probe of individual cells by spectral analysis of cell modes. Second, as scanning cytometer for rapidly probing large numbers of cells by pulse-height spectroscopy.
| Original language | English |
|---|---|
| Pages (from-to) | 103-104 |
| Number of pages | 2 |
| Journal | Conference Proceedings - Lasers and Electro-Optics Society Annual Meeting-LEOS |
| State | Published - 1996 |
| Event | Proceedings of the 1996 Conference on Lasers and Electro-Optics, CLEO'96 - Anaheim, CA, USA Duration: Jun 2 1996 → Jun 7 1996 |
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Electrical and Electronic Engineering