Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios: KOCOA project

Yuriko Katsumata; Hidemi Todoriki; Yasushi Higashiuesato; Shotoku Yasura; Yusuke Ohya; D. Craig Willcox; Hiroko H. Dodge

doi:10.3233/JAD-121138

Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios: KOCOA project

Yuriko Katsumata, Hidemi Todoriki, Yasushi Higashiuesato, Shotoku Yasura, Yusuke Ohya, D. Craig Willcox, Hiroko H. Dodge

Biostatistics

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

We cross-sectionally examined which lipid profiles are associated with better cognitive function among those aged 80 and older, free of dementia (Clinical Dementia Rating ≤0.5), functionally independent, and community-dwelling. Our cohort consisted of 193 participants from the 'Keys to Optimal Cognitive Aging (KOCOA) Project', a prospective cohort study in Okinawa, Japan. Higher low-density lipoprotein cholesterol levels and lower triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratios were associated with higher scores in memory performance after controlling for confounders. Further research is required to clarify the associations among LDL-C levels, TG/HDL-C ratios, and healthy cognitive aging.

Original language	English
Pages (from-to)	273-279
Number of pages	7
Journal	Journal of Alzheimer's Disease
Volume	34
Issue number	1
DOIs	https://doi.org/10.3233/JAD-121138
State	Published - 2013

Funding

Funders	Funder number
Japan Society for the Promotion of Science	23591220

Keywords

Aged 80 and over
lipoprotein cholesterol
memory disorders

ASJC Scopus subject areas

General Neuroscience
Clinical Psychology
Geriatrics and Gerontology
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3233/JAD-121138

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Katsumata, Y., Todoriki, H., Higashiuesato, Y., Yasura, S., Ohya, Y., Willcox, D. C., & Dodge, H. H. (2013). Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios: KOCOA project. Journal of Alzheimer's Disease, 34(1), 273-279. https://doi.org/10.3233/JAD-121138

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title = "Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios: KOCOA project",

abstract = "We cross-sectionally examined which lipid profiles are associated with better cognitive function among those aged 80 and older, free of dementia (Clinical Dementia Rating ≤0.5), functionally independent, and community-dwelling. Our cohort consisted of 193 participants from the 'Keys to Optimal Cognitive Aging (KOCOA) Project', a prospective cohort study in Okinawa, Japan. Higher low-density lipoprotein cholesterol levels and lower triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratios were associated with higher scores in memory performance after controlling for confounders. Further research is required to clarify the associations among LDL-C levels, TG/HDL-C ratios, and healthy cognitive aging.",

keywords = "Aged 80 and over, lipoprotein cholesterol, memory disorders",

author = "Yuriko Katsumata and Hidemi Todoriki and Yasushi Higashiuesato and Shotoku Yasura and Yusuke Ohya and Willcox, \{D. Craig\} and Dodge, \{Hiroko H.\}",

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language = "English",

volume = "34",

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Katsumata, Y, Todoriki, H, Higashiuesato, Y, Yasura, S, Ohya, Y, Willcox, DC & Dodge, HH 2013, 'Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios: KOCOA project', Journal of Alzheimer's Disease, vol. 34, no. 1, pp. 273-279. https://doi.org/10.3233/JAD-121138

Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios: KOCOA project. / Katsumata, Yuriko; Todoriki, Hidemi; Higashiuesato, Yasushi et al.
In: Journal of Alzheimer's Disease, Vol. 34, No. 1, 2013, p. 273-279.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios

T2 - KOCOA project

AU - Katsumata, Yuriko

AU - Todoriki, Hidemi

AU - Higashiuesato, Yasushi

AU - Yasura, Shotoku

AU - Ohya, Yusuke

AU - Willcox, D. Craig

AU - Dodge, Hiroko H.

PY - 2013

Y1 - 2013

N2 - We cross-sectionally examined which lipid profiles are associated with better cognitive function among those aged 80 and older, free of dementia (Clinical Dementia Rating ≤0.5), functionally independent, and community-dwelling. Our cohort consisted of 193 participants from the 'Keys to Optimal Cognitive Aging (KOCOA) Project', a prospective cohort study in Okinawa, Japan. Higher low-density lipoprotein cholesterol levels and lower triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratios were associated with higher scores in memory performance after controlling for confounders. Further research is required to clarify the associations among LDL-C levels, TG/HDL-C ratios, and healthy cognitive aging.

AB - We cross-sectionally examined which lipid profiles are associated with better cognitive function among those aged 80 and older, free of dementia (Clinical Dementia Rating ≤0.5), functionally independent, and community-dwelling. Our cohort consisted of 193 participants from the 'Keys to Optimal Cognitive Aging (KOCOA) Project', a prospective cohort study in Okinawa, Japan. Higher low-density lipoprotein cholesterol levels and lower triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratios were associated with higher scores in memory performance after controlling for confounders. Further research is required to clarify the associations among LDL-C levels, TG/HDL-C ratios, and healthy cognitive aging.

KW - Aged 80 and over

KW - lipoprotein cholesterol

KW - memory disorders

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U2 - 10.3233/JAD-121138

DO - 10.3233/JAD-121138

M3 - Article

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AN - SCOPUS:84874316117

SN - 1387-2877

VL - 34

SP - 273

EP - 279

JO - Journal of Alzheimer's Disease

JF - Journal of Alzheimer's Disease

IS - 1

ER -

Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios: KOCOA project

Abstract

Funding

Keywords

ASJC Scopus subject areas

UN SDGs

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