Virus-induced immunosuppression.

D. W. Horohov, B. T. Rouse

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


Infection with a variety of viruses results in the suppression of the host's immune system. Several mechanisms thought to be responsible for this effect are discussed: infection and alteration of lymphocytes and macrophages, production of soluble suppressor factors, and the induction of suppressor cells. The clinical significance of virus-induced immunosuppression is also discussed.

Original languageEnglish
Pages (from-to)1097-1127
Number of pages31
JournalThe Veterinary clinics of North America. Small animal practice
Issue number6
StatePublished - Nov 1986

Bibliographical note

Funding Information:
We thank Drs. Wyckoff, Norley, Wust, Potgieter, and Moore for thoughtful criticisms. The authors' research was supported by the NIH (AI 14981).

ASJC Scopus subject areas

  • Small Animals


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